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Effects of Skin Extracts from Arthus Reaction Sites on Collagen Synthesis by Cultured Fibroblasts Derived from Guinea Pig Skin
https://kwmed.repo.nii.ac.jp/records/175
https://kwmed.repo.nii.ac.jp/records/1757703ebec-64cd-462d-a76e-535b2849b583
名前 / ファイル | ライセンス | アクション |
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KJ00010221459.pdf (630.8 kB)
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-01-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of Skin Extracts from Arthus Reaction Sites on Collagen Synthesis by Cultured Fibroblasts Derived from Guinea Pig Skin | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
HATAMOCHI, Atsushi
× HATAMOCHI, Atsushi× TAKEDA, Koji× UEKI, Hiroaki |
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著者所属(英) | ||||||
en | ||||||
Department of Dermatology, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Dermatology, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Dermatology, Kawasaki Medical School | ||||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Active Arthus reaction | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Skin extracts | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Cultured fibroblasts | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Collagen synthesis | |||||
記事種別(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Original Article | |||||
抄録(英) | ||||||
en | ||||||
Active Arthus reactions were provoked by injecting bovine serum albumin (BSA) into the skin of sensitized guinea pigs. Total and collagenous protein synthesis was determined by treating cultured fibroblasts derived from guinea pig skin with skin extract from the injection sites at 90-minute intervals after challenge injections. The total protein synthesized was determined by the incorporation of radioactive proline, and the collagenous protein synthesized was measured by the incorporation of labeled hydroxyproline. Synthesis of both total and collagenous protein in the presence of the extract from sensitized guinea pig skin was higher than with extract from non-sensitized guinea pig skin. DNA synthesis was not affected by the extract from sensitized guinea pig skin. These findings suggest that collagen synthesis increases in the early phase of an Arthus reaction. | ||||||
書誌情報 |
en : Kawasaki medical journal 巻 12, 号 1, p. 35-40, 発行日 1986 |
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URL | ||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1986en/12(1)35-40.1986.pdf | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1986en/12(1)35-40.1986.pdf | |||||
識別子タイプ | URI | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/KMJ-E12(1)35 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-0234 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2434-3404 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00710169 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12029005 |