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Its usefulness for lymph node metastasis of lung cancer has been established; however, there are only a few reports regarding its usefulness for benign diseases. We aimed to investigate the clinical usefulness and potential problems of EBUS-TBNA for sarcoidosis. We retrospectively analyzed 67 patients with suspected sarcoidosis in our hospital between May 2004 and November 2016 and evaluated their diagnoses with EBUS-TBNA and other diagnostic methods (transbronchial lung biopsy(TBLB) or mediastinoscope). In all, 10 of 20 patients diagnosed sarcoidosis using EBUSTBNA exhibited bilateral hilar lymphadenopathy (BHL) on their chest X-rays. Targeted lymph nodes were #4 and/or #7. On average, the puncture distance was 27.9 ± 4.5 mm, with 19 cases having a puncture distance of \u003e20 mm. We could not examine 15 cases, 8 of which were stage III, 2 were stage Ⅱ , 1 case failed to identify the lymph node, 1 case for blood flow and 3 were stage 0. No adverse events were associated with EBUS-TBNA. Thus, EBUS-TBNA is a useful and safe procedure for diagnosing sarcoidosis with lymphadenopathy of the mediastinum and hilum."}]}, "item_10001_textarea_6": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_textarea_value": " 縦隔・肺門リンパ節病変に対する超音波気管支内視鏡ガイド下経気管支針生検(endobronchial ultrasound-guided transbronchial needle aspiration: 以下EBUS-TBNA) は,縦隔鏡や外科的な肺生検に比べ低侵襲である.肺癌のリンパ節転移の診断に対するEBUS-TBNAの有用性は確立されており,良性疾患に対する有用性や内視鏡所見についての報告は少ない.サルコイドーシスに対するEBUS-TBNA の有用性と問題点を検討した.川崎医科大学呼吸器内科に2004年5月1日から2016年11月30日に,サルコイドーシスの疑いで入院した67例(男34,女33)を対象とした.EBUS-TBNA でサルコイドーシスと診断した症例と,それ以外で診断した症例を後方視的に解析した.サルコイドーシスと診断したのは39/67例(58%),そのうちTBLB + EBUS-TBNA で診断;13/21例(62%),EBUS-TBNA のみで診断;2/2例,TBLB(transbronchial lung biopsy)のみで診断;22/41例(53%),縦隔鏡で診断;1例,皮膚生検で診断; 1例であった.受診の契機は健康診断の胸部エックス線検査で両側肺門リンパ節腫脹(bilateral hilar lymphadenopathy:以下BHL)等の胸部異常陰影の指摘によるものが約半数(31/67例)を占めていた.穿刺リンパ節は#4R と#7が多く,穿刺距離は 27.9±4.5 mm,そのうち19例は 20 mm 以上であった.EBUS-TBNA が施行できなかった15例のうち8例は病期Ⅲ,2例は病期Ⅱ,3例は病期0,1例は血流のため,1例はリンパ節が同定不可であった.また,EBUS-TBNA に関連した重篤な有害事象はなかった.縦隔・肺門リンパ節が腫大したサルコイドーシスでは,穿刺困難な事由がなければ,EBUS-TBNA による診断は有用である."}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "八十川, 直哉"}], "nameIdentifiers": [{"nameIdentifier": "109773", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "池田, 征樹"}], "nameIdentifiers": [{"nameIdentifier": "109774", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "大植, 祥弘"}], "nameIdentifiers": [{"nameIdentifier": "109775", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "黒瀬, 浩史"}], "nameIdentifiers": [{"nameIdentifier": "109776", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": 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サルコイドーシスの診断における超音波気管支内視鏡ガイド下経気管支針生検(EBUS-TBNA)の有用性
https://kwmed.repo.nii.ac.jp/records/2177
https://kwmed.repo.nii.ac.jp/records/2177336b5f07-06b6-40b4-81b8-1c36f9a27cd5
名前 / ファイル | ライセンス | アクション |
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PDF (3.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-04-01 | |||||
タイトル | ||||||
タイトル | サルコイドーシスの診断における超音波気管支内視鏡ガイド下経気管支針生検(EBUS-TBNA)の有用性 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Clinical usefulness of endobronchial ultrasound-guided transbronchial needle aspiration in sarcoidosis diagnosis | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
八十川, 直哉
× 八十川, 直哉× 池田, 征樹× 大植, 祥弘× 黒瀬, 浩史× 吉岡, 大介× 白井, 亮× 加藤, 茂樹× 小橋, 吉博× 小賀, 徹× 岡, 三喜男× YASOKAWA, Naoya× IKEDA, Masaki× OHUE, Yoshihiro× KUROSE, Koji× YOSHIOKA, Daisuke× SHIRAI, Ryo× KATO, Shigeki× KOBASHI, Yoshihiro× OGA, Toru× OKA, Mikio |
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著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
池田クリニック | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学呼吸器内科学 | ||||||
著者所属(日) | ||||||
川崎医科大学免疫腫瘍学 | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Ikeda clinic | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Respiratory Medicine, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Immuno-Oncology, Kawasaki Medical School | ||||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | サルコイドーシス | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 良性疾患 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 超音波気管支内視鏡ガイド下経気管支針生検 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 両側リンパ節腫大 | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Sarcoidosis, Benign disease | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Bilateral hilar lymphadenopathy (BHL) | |||||
抄録(日) | ||||||
縦隔・肺門リンパ節病変に対する超音波気管支内視鏡ガイド下経気管支針生検(endobronchial ultrasound-guided transbronchial needle aspiration: 以下EBUS-TBNA) は,縦隔鏡や外科的な肺生検に比べ低侵襲である.肺癌のリンパ節転移の診断に対するEBUS-TBNAの有用性は確立されており,良性疾患に対する有用性や内視鏡所見についての報告は少ない.サルコイドーシスに対するEBUS-TBNA の有用性と問題点を検討した.川崎医科大学呼吸器内科に2004年5月1日から2016年11月30日に,サルコイドーシスの疑いで入院した67例(男34,女33)を対象とした.EBUS-TBNA でサルコイドーシスと診断した症例と,それ以外で診断した症例を後方視的に解析した.サルコイドーシスと診断したのは39/67例(58%),そのうちTBLB + EBUS-TBNA で診断;13/21例(62%),EBUS-TBNA のみで診断;2/2例,TBLB(transbronchial lung biopsy)のみで診断;22/41例(53%),縦隔鏡で診断;1例,皮膚生検で診断; 1例であった.受診の契機は健康診断の胸部エックス線検査で両側肺門リンパ節腫脹(bilateral hilar lymphadenopathy:以下BHL)等の胸部異常陰影の指摘によるものが約半数(31/67例)を占めていた.穿刺リンパ節は#4R と#7が多く,穿刺距離は 27.9±4.5 mm,そのうち19例は 20 mm 以上であった.EBUS-TBNA が施行できなかった15例のうち8例は病期Ⅲ,2例は病期Ⅱ,3例は病期0,1例は血流のため,1例はリンパ節が同定不可であった.また,EBUS-TBNA に関連した重篤な有害事象はなかった.縦隔・肺門リンパ節が腫大したサルコイドーシスでは,穿刺困難な事由がなければ,EBUS-TBNA による診断は有用である. | ||||||
抄録(英) | ||||||
en | ||||||
Evaluation of lymphadenopathy of the mediastinum and hilum using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is comparatively less invasive than mediastinoscopy and surgical biopsy. Its usefulness for lymph node metastasis of lung cancer has been established; however, there are only a few reports regarding its usefulness for benign diseases. We aimed to investigate the clinical usefulness and potential problems of EBUS-TBNA for sarcoidosis. We retrospectively analyzed 67 patients with suspected sarcoidosis in our hospital between May 2004 and November 2016 and evaluated their diagnoses with EBUS-TBNA and other diagnostic methods (transbronchial lung biopsy(TBLB) or mediastinoscope). In all, 10 of 20 patients diagnosed sarcoidosis using EBUSTBNA exhibited bilateral hilar lymphadenopathy (BHL) on their chest X-rays. Targeted lymph nodes were #4 and/or #7. On average, the puncture distance was 27.9 ± 4.5 mm, with 19 cases having a puncture distance of >20 mm. We could not examine 15 cases, 8 of which were stage III, 2 were stage Ⅱ , 1 case failed to identify the lymph node, 1 case for blood flow and 3 were stage 0. No adverse events were associated with EBUS-TBNA. Thus, EBUS-TBNA is a useful and safe procedure for diagnosing sarcoidosis with lymphadenopathy of the mediastinum and hilum. | ||||||
書誌情報 |
川崎医学会誌 en : Kawasaki medical journal 巻 45, p. 95-100, 発行日 2019 |
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出版者 | 川崎医学会 | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0386-5924 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2758-089X | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00045593 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN12940574 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/KMJ-J201945095 | |||||
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内容記述タイプ | Other | |||||
内容記述 | 原著論文 | |||||
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内容記述タイプ | Other | |||||
内容記述 | Regular Article | |||||
医中誌ID | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | ICHUSHI | |||||
関連識別子 | 2020200382 | |||||
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識別子タイプ | URI | |||||
関連識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2019/KMJ-J201945095.pdf | |||||
関連名称 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2019/KMJ-J201945095.pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |