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Twenty-four hours following the injection, functional activities of the classical (CH50) and alternative complement pathways (APCH50), and the complement component C3 concentrations in the sera were significantly reduced in the Cd-treated rats. Histopathological examinations of the livers and kidneys, as well as laboratory tests for serum transaminases (SGOT, SGPT) and serum urea nitrogen (SUN), revealed that cadmium acetate induced moderate to severe hepatic injury depending on the dose administered, whereas kidney lesions were less evident. 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In Vivo Effects of Cadmium Acetate on Rat Complement
https://kwmed.repo.nii.ac.jp/records/236
https://kwmed.repo.nii.ac.jp/records/236c6198da8-0454-4675-9dd8-da032876c72c
名前 / ファイル | ライセンス | アクション |
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KJ00010217559.pdf (1.8 MB)
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-01-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | In Vivo Effects of Cadmium Acetate on Rat Complement | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
MOCHIZUKI, Yoshio
× MOCHIZUKI, Yoshio× KIKUCHI, Kazuko× UEKI, Ayako |
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著者所属(英) | ||||||
en | ||||||
Department of Hygiene, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Hygiene, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of Hygiene, Kawasaki Medical School | ||||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | cadmiun | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | rat complement | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | hepatic injury | |||||
抄録(英) | ||||||
en | ||||||
Male Wistar rats were injected intraperitoneally or intravenously with various doses of cadmium acetate (i.p.: 1 mg, 2 mg or 4 mg Cd/kg body weight, i.v.: 1 mg, 2 mg or 3 mg Cd/kg body weight). Twenty-four hours following the injection, functional activities of the classical (CH50) and alternative complement pathways (APCH50), and the complement component C3 concentrations in the sera were significantly reduced in the Cd-treated rats. Histopathological examinations of the livers and kidneys, as well as laboratory tests for serum transaminases (SGOT, SGPT) and serum urea nitrogen (SUN), revealed that cadmium acetate induced moderate to severe hepatic injury depending on the dose administered, whereas kidney lesions were less evident. | ||||||
書誌情報 |
en : Kawasaki medical journal 巻 14, 号 1, p. 37-41, 発行日 1988 |
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URL | ||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1988en/14(1)37-41.1988.pdf | |||||
識別子タイプ | URI | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/KMJ-E14(1)37 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0385-0234 | |||||
ISSN | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2434-3404 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00710169 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12029005 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |