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Effects of Partial Isolation on Mice Behavior
https://kwmed.repo.nii.ac.jp/records/3059
https://kwmed.repo.nii.ac.jp/records/3059117209a7-138f-4786-bea1-a3a1f27255bf
| 名前 / ファイル | ライセンス | アクション |
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PDF (1.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||
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| 公開日 | 2023-03-10 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Effects of Partial Isolation on Mice Behavior | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 著者 |
TAKAHASHI, Yu
× TAKAHASHI, Yu
× UENO, Hiroshi
× WANI, Kenta
× MURAKAMI, Shinji
× ISHIHARA, Takeshi
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| 著者所属(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Department of Psychiatry, Kawasaki Medical School | |||||||||||||||
| 著者所属(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Department of Medical Technology, Kawasaki University of Medical Welfare | |||||||||||||||
| 著者所属(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Department of Psychiatry, Kawasaki Medical School | |||||||||||||||
| 著者所属(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Department of Psychiatry, Kawasaki Medical School | |||||||||||||||
| 著者所属(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Department of Psychiatry, Kawasaki Medical School | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Social withdrawal | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Sociability | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Anxiety and depressive like behaviour | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Social isolation | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Partial isolation | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Stress | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Group housing | |||||||||||||||
| キーワード | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | Animal model | |||||||||||||||
| 抄録(英) | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 値 | Background: The effects of an isolated human environment with little societal contact are a topic of interest in clinical psychiatry. Studies using animal models are important for investigating the effects of such an environment. Considering that the modern human environment that allows partial and limited communication even for those who are isolated from the society, raising mice in social isolation, a method that has been conventionally adopted with mice, is not an accurate simulation. Method: Therefore, in our experiment, to better simulate the partial isolation that is often observed in humans, we devised a method of dividing the breeding cage into two compartments using a transparent sheet, raising four mice in one section and a single mouse in the other (we defined it as physical isolation). We then compared the behavioral patterns of group-reared, conventionally socially isolated, and physically isolated mice to determine the effects of limited communication restrictions on individual mice. Result: When the new rearing method of physical isolation was adopted, there was no significant difference in the time spent around cages with and without familiar mice, or around cages with strange mice and cages with familiar mice, as observed in group rearing, confirming that social behavior is suppressed in the same way as in social isolation. However, there was no significant increase in immobility time on the forced swim test or tail suspension test, as observed in social isolation, suggesting no increase in anxiety or depression. In the cotton bud biting test, the number of attacks was significantly lower than the other two rearing methods, confirming a decrease in aggression. Conclusion: Our findings, which show that mice placed in such an environment may experience less stress than when being raised in groups, despite suffering problems with their development of sociability, are of considerable interest. |
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| 書誌情報 |
en : Kawasaki medical journal 巻 48, p. 105-117, 発行日 2022 |
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| 出版者 | ||||||||||||||||
| 出版者 | Kawasaki Medical Society | |||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||
| 収録物識別子 | 24343404 | |||||||||||||||
| 書誌レコードID | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AA12029005 | |||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||
| 関連識別子 | https://doi.org/10.11482/KMJ-E202248105 | |||||||||||||||
| 記事種別(英) | ||||||||||||||||
| 内容記述 | Regular Article | |||||||||||||||
| 言語 | en | |||||||||||||||
| 関連サイト | ||||||||||||||||
| 識別子タイプ | URI | |||||||||||||||
| 関連識別子 | https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2022en/KMJ-E202248105.pdf | |||||||||||||||
| 著者版フラグ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
