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Monoamine Interaction : Effects of Long-Term Treatments with L-tryptophan and Setiptiline Maleate on Rat Brain a2- and β-adrenergic Receptor
https://kwmed.repo.nii.ac.jp/records/324
https://kwmed.repo.nii.ac.jp/records/3241a7645f9-0aa1-4161-ac8f-34e122a79345
名前 / ファイル | ライセンス | アクション |
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KJ00010210219.pdf (789.1 kB)
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-01-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Monoamine Interaction : Effects of Long-Term Treatments with L-tryptophan and Setiptiline Maleate on Rat Brain a2- and β-adrenergic Receptor | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
KATSUDA, Yoshiaki
× KATSUDA, Yoshiaki |
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著者所属(英) | ||||||
en | ||||||
Department of Psychiatry, Kawasaki Medical School | ||||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | L-tryptophan | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Setiptiline Maleate | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | β-down regulation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | α2-dowm regulation | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Monoamine interaction | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Long-term treatment | |||||
記事種別(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Original Article | |||||
言語 | en | |||||
抄録(英) | ||||||
en | ||||||
The role of serotonin precursor L-tryptophan and the new tetracyclic antidepressant Setiptiline Maleate in the regulation of β-and α2-adrenergic receptor was examined by Radio Receptor Assay method. Treatment with either L-tryptophan (300 mg/kg, twice, daily) or Setiptiline Maleate (3 mg/kg, twice, daily) for 14 days caused a significant decrease in the number of β-adrenergic receptors (Bmax) measured 12 hours after the last dose. Treatment with co-administration of both L-tryptophan and Setiptiline caused no significant difference from that of either L-tryptophan or Setiptiline alone. Treatment with Setiptiline caused a significant decrease in the number of α2-adrenergic receptor (Bmax), but treatment with L-tryptophan caused no change in it. Treatment with co-administration of both Setiptiline and L-tryptophan potentiated the decrease in the number of α2-adrenergic receptors compared with single administration of Setiptiline alone. | ||||||
書誌情報 |
en : Kawasaki medical journal 巻 17, 号 1-4, p. 37-45, 発行日 1991 |
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URL | ||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1991en/17(1.2.3.4)37-45.1991.pdf | |||||
識別子タイプ | URI | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/KMJ-E17(1.2.3.4)37-45.1991 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0385-0234 | |||||
ISSN | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2434-3404 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00710169 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12029005 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |