{"created":"2023-06-19T10:29:32.083213+00:00","id":1641,"links":{},"metadata":{"_buckets":{"deposit":"012a0761-b51a-418e-ae58-2af561de048a"},"_deposit":{"created_by":31,"id":"1641","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"1641"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00001641","sets":["1709617079800:35:307:556"]},"author_link":[],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"107","bibliographicPageStart":"101","bibliographicVolumeNumber":"39","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"症例報告","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2013/KMJ39(3)101-107.2013.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/2013/KMJ39(3)101-107.2013.pdf","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00045593","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AN12940574","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-5924","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2758-089X","subitem_source_identifier_type":"EISSN"}]},"item_3_text_6":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Neurology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology, Kawasaki Medical School"}]},"item_3_textarea_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"今回われわれは,発症4年目から6年間の経過を観察しえた原発性進行性失語(PPA)の1例を経験した.症例は63歳女性.55歳頃から言葉が出にくい,詰まる,速くしゃべれないことを自覚し,徐々に進行するため58歳時に当科を受診した.60歳時よりたどたどしい会話となり,電話では「外国の方ですか」と問われた.塩酸ドネペジルを処方されたが,その後も症状は進行し,電話番号を暗記できなくなったため,62歳時に当科へ入院した.発話は非流暢で,音韻性錯語が目立った.また,プロソディー障害,失文法,Foreign accent syndrome,アナルトリー障害を認めた.本例の発話障害の特徴と123I-IMP SPECT所見の検討から,縁上回病変による音韻障害と概念の音韻系列の実現障害が主体で,そこに中前頭回病変によるプロソディー障害,下前頭回病変による失文法とForeign accent syndrome,中心前回病変のアナルトリー障害が徐々に加わって進行していると考えた.本例では発症9年目の現時点でも意味システムが比較的保たれており,今後の経過が注目される."}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"We report the case of a 62-year-old woman with primary progressive aphasia (PPA). We performed a 6-year follow-up assessment corresponding changes in magnetic resonance imaging (MRI) and ^<123>I-IMP SPECT findings. Linguistic examination showed a severe impairment in repetition, as well as fluent spontaneous speech with phonemic paraphasia, anarthria, foreign accent syndrome and agraphia. Brain MRI showed very mild atrophy of the left frontal lobe, parietal lobe, and temporal lobes. ^<123>I-IMP SPECT showed that the temporoparietal lobe was the most severely affected region. Key neuropsychological features in this case were impairments of the phonological system. We speculate that the characteristic feature of aphasia may result from dysfunction of the left supramarginal gyrus in this patient."}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"久徳, 弓子","creatorNameLang":"ja"},{"creatorName":"クトク, ユミコ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"砂田, 芳秀","creatorNameLang":"ja"},{"creatorName":"スナダ, ヨシヒデ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"Kutoku, Yumiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sunada, Yoshihide","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00008794459.pdf","filesize":[{"value":"848.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00008794459.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/1641/files/KJ00008794459.pdf"},"version_id":"64c1e548-cb23-4837-93d0-147a45a43ba5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"進行性失語","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"PPA","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Primary progressive aphasia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PPA","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"発話障害が緩徐に進行する63歳女性の臨床経過・画像所見の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"発話障害が緩徐に進行する63歳女性の臨床経過・画像所見の検討","subitem_title_language":"ja"},{"subitem_title":"A clinical, neuropsychological, and radiological study of a case with Primary Progressive Aphasia.","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["556"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"1641","relation_version_is_last":true,"title":["発話障害が緩徐に進行する63歳女性の臨床経過・画像所見の検討"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-10-11T04:46:46.165370+00:00"}