{"created":"2023-06-19T10:29:46.626257+00:00","id":1883,"links":{},"metadata":{"_buckets":{"deposit":"1f2c6691-bcd2-4e95-9666-999b315d9308"},"_deposit":{"created_by":31,"id":"1883","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"1883"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00001883","sets":["1709617079800:35:604:605"]},"author_link":["110467","110468","110469","110470","110471","110472","110473","110474","110475","110476","110477","110478","110479","110480","110481","110482","110483","110484"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"62","bibliographicPageStart":"57","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_10001_description_33":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"症例報告","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10001_description_34":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Case Report","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"川崎医学会","subitem_publisher_language":"ja"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-J43(1)57","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2017/KMJ-J43(1)57.pdf","subitem_relation_type_select":"URI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00045593","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AN12940574","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-5924","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2758-089X","subitem_source_identifier_type":"EISSN"}]},"item_10001_text_31":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学血液内科学"}]},"item_10001_text_32":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hematology, Kawasaki Medical School"}]},"item_10001_textarea_5":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"Angioimmunoblastic T cell lymphoma (AITL) is a T cell-related tumor that is classified as a peripheral T cell/natural killer cell tumor according to the new World Health Organization classification. AITL shows various clinical features owing to the cytokines produced directly or indirectly by tumor cells and includes a variety of symptoms, such as general lymphadenopathy, hepatosplenomegaly, fever, and polyclonal hypergammaglobulinemia. AITL is often accompanied by reactive plasmacytosis, and it has been reported that AITL can be complicated by pure red cell aplasia. Here, we report an 80-year-old woman with AITL who was suspected to have a plasma cell tumor by cytological diagnosis of hydrothorax. The patient presented with exacerbated asthmatic symptoms as well as exanthema over her entire body. Moreover, during treatment for bronchial asthma at a local doctor’s clinic, hydrothorax in both lungs and high C-reactive protein levels were observed. She was referred to our hospital for detailed examination and treatment. Blood test results revealed anemia as well as a high proportion of plasma cell-like atypical lymphocytes in the peripheral blood. Specimens of the hydrothorax also contained CD138-positive plasma cells of varying sizes; however, there was no evidence of deviation in light chain limitation. We did not notice elevated plasma cell counts, and the patient was considered to have pure red cell aplasia based on the results of the marrow examination. However, we noted a subcutaneous mass under her shoulder blade. An excisional biopsy was performed, and she was diagnosed with AITL. The patient was considered to have hydrothorax with plasmacytosis as a reaction to AITL. As seen in our case, AITL may cause pleural effusions along with reactive plasmacytosis and pure red cell aplasia."}]},"item_10001_textarea_6":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"血管免疫芽球性Ｔ細胞リンパ腫（angioimmunoblastic T-cell lymphoma: AITL）は新WHO分類において末梢Ｔ細胞 / NK 細胞腫瘍に分類されているＴ細胞性腫瘍である．その臨床像は，全身リンパ節腫大，肝脾腫，発熱，多クローン性高γ グロブリン血症など多様な症状を呈することが知られている．今回，我々は胸水細胞診で形質細胞腫が疑われたAITL を経験したので報告する．症例は80歳代の女性．近医にて気管支喘息治療中に，喘息症状が悪化し，全身の皮疹が出現．両側胸水貯留，CRP 高値が出現したため，精査治療目的で当院紹介となった．血液検査で貧血を認め，末梢血に形質細胞様の異型リンパ球を10％認めた．胸水には大小不同のCD138陽性形質細胞を多数認め細胞診で形質細胞腫が疑われたが，胸水セルブロックではκ・λ の軽鎖制限を認めなかった．骨髄検査では，形質細胞の増加を認めず赤芽球癆の状態であった．皮下腫瘤を生検した結果，AITL と診断した．AITL は，腫瘍細胞が直接的・間接的にサイトカインを産生し，それに起因した多彩な臨床像を呈する．そのため，AITL は反応性に形質細胞の増加を伴うことが多く，本症例は，反応性に胸水中に形質細胞の増加を伴ったと考えられた．また，AITL は赤芽球癆を合併することも報告されている．AITL では，反応性の形質細胞増多を伴う胸水貯留や赤芽球癆をきたす場合があることに注意すべきである． "}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐野, 史典","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田, 聖子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"竹内, 麻子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"徳永, 博俊","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"近藤, 敏範","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松橋, 佳子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"中西, 秀和","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"和田, 秀穂","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"杉原, 尚","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SANO, Fuminori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMADA, Seiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKEUCHI, Asako","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TOKUNAGA, Hirotoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KONDO, Toshinori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUHASHI, Yoshiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKANISHI, Hidekazu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"WADA, Hideho","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SUGIHARA, Takashi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-28"}],"displaytype":"detail","filename":"KMJ-J43(1)57.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/1883/files/KMJ-J43(1)57.pdf"},"version_id":"6a25a6f4-c6a8-4312-8796-5cac795b7b27"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"血管免疫芽球性Ｔ細胞リンパ腫","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"形質細胞腫","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"胸水細胞診","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Angioimmunoblastic T-cell lymphoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Plasmacytoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Pleural effusion cytology","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"胸水細胞診で形質細胞腫が疑われた血管免疫芽球性Ｔ細胞リンパ腫","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胸水細胞診で形質細胞腫が疑われた血管免疫芽球性Ｔ細胞リンパ腫","subitem_title_language":"ja"},{"subitem_title":"AITL suspected to have plasmacytoma by pleural effusion cytology","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"31","path":["605"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-09-28"},"publish_date":"2017-09-28","publish_status":"0","recid":"1883","relation_version_is_last":true,"title":["胸水細胞診で形質細胞腫が疑われた血管免疫芽球性Ｔ細胞リンパ腫"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2024-04-15T07:26:01.048485+00:00"}