{"created":"2023-06-19T10:29:50.260028+00:00","id":1940,"links":{},"metadata":{"_buckets":{"deposit":"723148cb-ac9e-4d7d-9407-35000356f94f"},"_deposit":{"created_by":31,"id":"1940","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"1940"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00001940","sets":["1709617079800:35:616:623"]},"author_link":["110381","110382","110383","110384","110385","110386","110387","110388"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"155","bibliographicPageStart":"151","bibliographicVolumeNumber":"44","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_10001_description_33":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description_type":"Other"}]},"item_10001_description_34":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Morning Case Conference","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"川崎医学会","subitem_publisher_language":"ja"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-J44(2)151","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2018/KMJ-J44(2)151.pdf","subitem_relation_type_select":"URI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00045593","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AN12940574","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-5924","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2758-089X","subitem_source_identifier_type":"EISSN"}]},"item_10001_text_31":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属病院臨床教育研修センター"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学リウマチ・膠原病学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学リウマチ・膠原病学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学リウマチ・膠原病学"}]},"item_10001_text_32":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Medical Education and Training, Kawasaki Medical School Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department of Rheumatology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Rheumatology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Rheumatology, Kawasaki Medical School"}]},"item_10001_textarea_5":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"　Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder which is responsible for a significant proportion of cases of fever of unknown origin. This disease is characterized by high spiking fevers, musculoskeletal disorders and salmon-colored rash. Here we report the case of a 57-year-old woman with fever of unknown origin who was diagnosed with AOSD. Hyperferritinemia contributed to her diagnosis. The patient was referred to our clinic with persistent spike fevers and arthralgia for 3 weeks despite antibiotic treatment. The patient also had a sore throat, and developed a skin rush on her trunk upon admission. Laboratory data indicated leukocytosis (11,480 /μL), elevated levels of CRP (12.98 mg/dL), and hyperferritinemia (5,511 ng/mL). To exclude infections and malignant diseases, systemic computed tomography scans and biopsy from bone marrow and skin were performed. From these examinations, and based on the criteria set by Yamaguchi et al. , the patient was given a diagnosis of AOSD. She was started on prednisone and methotrexate, and these treatments were effective. Serum ferritin levels should be checked for the evaluation of fever of unknown origin."}]},"item_10001_textarea_6":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"　成人Still 病は弛張熱，関節炎，発熱時に増強する発疹（サーモンピンク疹）を３徴とする疾患で，白血球増加，血清CRP やフェリチン値の上昇などの強い炎症所見を認め，しばしば不明熱の原因となる．高フェリチン血症を契機に成人Still 病と診断した症例を経験したので報告する．患者は57歳女性，入院３週間前から発熱とともに咽頭痛，関節痛が出現し，近医にて抗菌薬治療が行われた．抗菌薬不応の発熱で当院を紹介受診し，不明熱精査目的に入院した．入院時より前胸部や背部に淡い紅斑が出現し，採血で，白血球増加（11,480/μL），CRP 高値（12.98 mg/dL），フェリチン著明高値（5,511 ng/mL）を認めた．胸腹部CT 検査では腋窩・鼠径リンパ節の腫脹と脾腫大を認めた．血液培養検査は陰性で，骨髄生検や皮膚生検にて造血器腫瘍を示唆する所見を認めなかった．感染症や悪性腫瘍を除外し，Yamaguchi らの分類基準を満たし，成人Still 病と診断した．プレドニゾロンとメトトレキサートの併用療法を開始したところ，速やかに全身状態は改善した．不明熱の原因検索を行う際に，フェリチン値の測定は有用であると考えられる．"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"古川, 芽衣","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"赤木, 貴彦","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"藤田, 俊一","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"守田, 吉孝","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FURUKAWA, Mei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"AKAGI, Takahiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUJITA, Shunichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MORITA, Yoshitaka","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-04"}],"displaytype":"detail","filename":"KMJ-J44(2)151.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/1940/files/KMJ-J44(2)151.pdf"},"version_id":"c284831c-f50f-4728-88bf-4e0227199ea4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"高フェリチン血症","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"成人Still 病","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"不明熱","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"adult-onset Still’s disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"fever of unknown origin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hyperferritinemia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"高フェリチン血症を契機に成人Still 病と診断した不明熱症例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"高フェリチン血症を契機に成人Still 病と診断した不明熱症例","subitem_title_language":"ja"},{"subitem_title":"Adult-onset Still’s disease as the cause of fever of unknown origin with hyperferritinemia","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"31","path":["623"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-04-04"},"publish_date":"2019-04-04","publish_status":"0","recid":"1940","relation_version_is_last":true,"title":["高フェリチン血症を契機に成人Still 病と診断した不明熱症例"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2024-04-13T02:55:20.728897+00:00"}