| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
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|
タイトル |
Action of Enzymes from Clostridium tertium A on the Group A Antigenic Determinant of Human Erythrocytes |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
TOMITA, Masafumi
MINE, Hiroko
OKUYAMA, Toshiko
SHIMOSATO, Kazuaki
IJIRI, Iwao
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| 著者所属(英) |
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|
en |
|
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Department of Legal Medicine, Kawasaki Medical School |
| 著者所属(英) |
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|
en |
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Department of Microbiology, Kawasaki Medical School |
| 著者所属(英) |
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|
en |
|
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Department of Legal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Department of Legal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Department of Legal Medicine, Kawasaki Medical School |
| キーワード |
|
|
言語 |
en |
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主題Scheme |
Other |
|
主題 |
ABO blood groups |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
A1 and A2 erythrocytes |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
A-antigenicity |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
A-decomposing enzyme |
| 記事種別(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Original Article |
|
言語 |
en |
| 抄録(英) |
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|
en |
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It is well known that Clostridium tertium A produces Adecomposing enzymes. We investigated the changes in ABO-antigenicity of human erythrocytes caused by the culture filtrate from this bacteria. Group A erythrocytes were specifically affected, and a decrease in A-activity and an enhancement of H-activity were observed. No change was observed on group B and O cells. There was a significant difference between the agglutinabilities of group A1 and A2 erythrocytes treated with Cl. tertium culture filtrate. A2 erythrocytes completely lost their agglutinability against undiluted anti-A sera. In contrast, A1 erythrocytes preserved a low Aantigenicity. It was clear that this difference reflected the heterogenous nature of A-antigenicity on group A cell membranes. On the other hand, it was suggested that the A-decomposing enzymes in the culture filtrate also had a heterogenous nature. Our crude enzyme preparation was completely inhibited by D-galactosamine, and weakly by N-acetyl-Dgalactosamine or D-galactose. Further enzyme purification was required to elucidate the differences in the antigenic determinants or the structural basis between A1 and A2 erythrocytes. |
| 書誌情報 |
en : Kawasaki medical journal
巻 13,
号 1,
p. 7-18,
発行日 1987
|
| URL |
|
|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1987en/13(1)7-18.1987.pdf |
|
識別子タイプ |
URI |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.11482/KMJ-E13(1)7 |
| ISSN |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0385-0234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
KJ00010218259.pdf (5.0 MB)
