{"created":"2023-06-19T10:28:02.596213+00:00","id":201,"links":{},"metadata":{"_buckets":{"deposit":"9445e109-4d04-47e9-a340-f5d5be4a1a87"},"_deposit":{"created_by":31,"id":"201","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"201"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000201","sets":["1709617079800:37:66:351"]},"author_link":[],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1987","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"18","bibliographicPageStart":"7","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original Article","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1987en/13(1)7-18.1987.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-E13(1)7 ","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00710169","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0234","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2434-3404","subitem_source_identifier_type":"EISSN"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Legal Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Microbiology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Legal Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Legal Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Legal Medicine, Kawasaki Medical School"}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"It is well known that Clostridium tertium A produces Adecomposing enzymes. We investigated the changes in ABO-antigenicity of human erythrocytes caused by the culture filtrate from this bacteria. Group A erythrocytes were specifically affected, and a decrease in A-activity and an enhancement of H-activity were observed. No change was observed on group B and O cells. There was a significant difference between the agglutinabilities of group A1 and A2 erythrocytes treated with Cl. tertium culture filtrate. A2 erythrocytes completely lost their agglutinability against undiluted anti-A sera. In contrast, A1 erythrocytes preserved a low Aantigenicity. It was clear that this difference reflected the heterogenous nature of A-antigenicity on group A cell membranes. On the other hand, it was suggested that the A-decomposing enzymes in the culture filtrate also had a heterogenous nature. Our crude enzyme preparation was completely inhibited by D-galactosamine, and weakly by N-acetyl-Dgalactosamine or D-galactose. Further enzyme purification was required to elucidate the differences in the antigenic determinants or the structural basis between A1 and A2 erythrocytes. "}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TOMITA, Masafumi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"MINE, Hiroko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"OKUYAMA, Toshiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"SHIMOSATO, Kazuaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"IJIRI, Iwao","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00010218259.pdf","filesize":[{"value":"5.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00010218259.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/201/files/KJ00010218259.pdf"},"version_id":"4d696dd5-76ad-487e-8923-e8812a5664d0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ABO blood groups","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"A1 and A2 erythrocytes","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"A-antigenicity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"A-decomposing enzyme","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Action of Enzymes from Clostridium tertium A on the Group A Antigenic Determinant of Human Erythrocytes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Action of Enzymes from Clostridium tertium A on the Group A Antigenic Determinant of Human Erythrocytes","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["351"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"201","relation_version_is_last":true,"title":["Action of Enzymes from Clostridium tertium A on the Group A Antigenic Determinant of Human Erythrocytes"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-09-26T05:36:23.951190+00:00"}