{"created":"2023-06-19T10:30:04.847657+00:00","id":2171,"links":{},"metadata":{"_buckets":{"deposit":"c76e5a73-d739-403d-a791-bf20d7edb5d3"},"_deposit":{"created_by":31,"id":"2171","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"2171"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00002171","sets":["1709617079800:35:686"]},"author_link":["109683","109684","109685","109686","109687","109688","109689","109690","109691","109692","109693","109694","109695","109696","109697","109698","109699","109700","109701","109702","109703","109704","109705","109706"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"61","bibliographicPageStart":"55","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical 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of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"}]},"item_10001_textarea_5":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"　Overactive bladder (OAB) involves lower urinary tract symptoms such as urinary urgency and polyuria, and tends to increase with age. In Japan, the drugs recommended and used for treatment of OAB patients are anticholinergic agents and β3 adrenalin receptor agonists. The present study was a retrospective investigation of the rates of long-term administration of anticholinergic agents and β3 adrenalin receptor agonists, adverse effects with these drugs, and reasons for discontinuation of administration, with female OAB patients. The subjects were 87 female patients who were examined at this hospital's Urology Dept. over 1 year between January and December 2013, and diagnosed as having OAB for the first time. With respect to the rates of long-term administration, in the β3 adrenalin receptor agonist group the rates of administration for 12 and 60 months, respectively, were 38.8% and 18.1%, and these rates in the anticholinergic agent group were 18.4% and 7.9%, so the long-term administration rates were somewhat higher in the β3 adrenalin receptor agonist group, but no difference between the groups was found. Adverse effects were more frequent in the anticholinergic agent group, with 17 subjects in that group (44.7%) developing buccal dryness, and 15 (39.5%) developing constipation. In both groups, the most frequent reason for discontinuation of administration was spontaneous remission."}]},"item_10001_textarea_6":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"　過活動膀胱（overactive bladder：以下OAB）は，尿意切迫感や頻尿などの下部尿路症状を有し，加齢とともに増加する傾向がある．OAB 患者の治療薬として，本邦では抗コリン薬とβ3アドレナリン受容体作動薬が推奨，使用されている．今回，女性OAB 患者に対する，抗コリン薬とβ3アドレナリン受容体作動薬の内服継続率，副作用，内服中止理由に関してretrospective に検討した．対象は，2013年１月から12月の１年間に当院泌尿器科を受診した初診の女性OAB 患者，87名とした．β3アドレナリン受容体作動薬投与群と抗コリン薬投与群の内服継続率は，β3アドレナリン受容体作動薬投与群は，12か月で38.8％，60か月で18.1％，抗コリン薬投与群は，12か月18.4%，60か月で7.9％であり，β3アドレナリン受容体作動薬投与群の方が若干継続率は良いものの，両群間に差は認めなかった．副作用に関しては，抗コリン薬投与群の方が多く，口喝が17例（44.7%），便秘が15例（39.5%）であった．薬剤中止の理由は両群とも自然寛解によるものが多かった．"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"藤井, 智浩","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109683","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大平, 伸","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109684","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"覺前, 蕉","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109685","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"森中, 啓文","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109686","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西下, 憲文","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109687","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"髙崎, 宏靖","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109688","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"杉山, 星哲","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109689","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"月森, 翔平","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109690","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"清水, 真次朗","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109691","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原, 綾英","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109692","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"宮地, 禎幸","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109693","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"永井, 敦","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"109694","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"FUJII, Tomohiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109695","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OHIRA, Shin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109696","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KAKUMAE, Sho","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109697","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MORINAKA, Hirofumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109698","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NISHISHITA, Norifumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109699","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TAKASAKI, Hiroyasu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109700","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SUGIYAMA, Seitetsu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109701","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TSUKIMORI, Syohei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109702","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SHIMIZU, Shinjiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109703","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HARA, Ryoei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109704","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MIYAJI, Yoshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109705","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NAGAI, Atsushi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"109706","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-04-01"}],"displaytype":"detail","filename":"KMJ-J201945055.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/2171/files/KMJ-J201945055.pdf"},"version_id":"b7ebc0fb-d5ac-4517-bb3c-37c3d1c50b1e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"女性","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"過活動膀胱","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"内服継続率","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Women","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Overactive bladder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Oral continuation rate","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"当院の女性過活動膀胱患者における抗コリン薬とβ3アドレナリン受容体作動薬の内服継続率に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"当院の女性過活動膀胱患者における抗コリン薬とβ3アドレナリン受容体作動薬の内服継続率に関する検討","subitem_title_language":"ja"},{"subitem_title":"Study on oral continuation rate of anticholinergic drugs and β3 adrenalin receptor agonists in women overactive bladder patients in our hospital","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"31","path":["686"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-04-01"},"publish_date":"2020-04-01","publish_status":"0","recid":"2171","relation_version_is_last":true,"title":["当院の女性過活動膀胱患者における抗コリン薬とβ3アドレナリン受容体作動薬の内服継続率に関する検討"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2024-04-19T04:11:01.757221+00:00"}