| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2022-10-21 |
| タイトル |
|
|
タイトル |
Perioperative therapy for non-small cell lung cancer - Current status and future perspective - |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
NAKATA, Masao
NOJIMA, Yuji
SAISHO, Shinsuke
KUROSAKI, Takeshi
SHIMIZU, Katsuhiko
|
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of General Thoracic Surgery, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of General Thoracic Surgery, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of General Thoracic Surgery, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of General Thoracic Surgery, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of General Thoracic Surgery, Kawasaki Medical School |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Non-small cell lung cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Surgery |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Adjuvant therapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Induction therapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Immune checkpoint inhibitor |
| 抄録(英) |
|
|
言語 |
en |
|
値 |
Lung cancer is the leading cause of cancer-related death. Surgery has been playing a pivotal role in the treatments with curative intent for non-small cell lung cancer (NSCLC). However, the outcome after surgery alone remains unsatisfactory. During the last two decades, several attempts have been made to improve the postoperative outcome. Metaanalysis demonstrated that adjuvant cisplatin-based chemotherapy achieved 4-5% of benefit in the 5-year survival as compared to surgery alone. Preoperative induction chemotherapy also yielded a 5% improvement of the 5-year survival rate, showing a similar efficacy with adjuvant chemotherapy. Induction chemoradiotherapy enhanced local control, whereas it was not associated with any survival benefit. Recently, the development of new drugs, such as tyrosine kinase inhibitors and immune checkpoint inhibitors, represents a major treatment advance for patients with lung cancer. Several attempts have been made to apply these drugs to perioperative treatments.
In this review, we sought to summarize the developments of perioperative therapy in the treatments of NSCLC, and discuss the future perspectives. |
| 書誌情報 |
en : Kawasaki medical journal
巻 46,
p. 59-72,
発行日 2020
|
| 出版者 |
|
|
出版者 |
Kawasaki Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03850234 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
24343404 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12685295 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.11482/KMJ-E202046059 |
| 記事種別(英) |
|
|
内容記述 |
Review |
| 医中誌ID |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
ICHUSHI |
|
|
関連識別子 |
2022017986 |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2020en/KMJ-E202046059.pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
PDF (764.2 kB)
