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  1. 川崎医学会機関誌
  2. Kawasaki Medical Journal
  3. Vol.46(2020)

Perioperative therapy for non-small cell lung cancer - Current status and future perspective -

https://kwmed.repo.nii.ac.jp/records/2924
https://kwmed.repo.nii.ac.jp/records/2924
55fdeb47-635b-4127-84b6-16e279113144
名前 / ファイル ライセンス アクション
KMJ-E202046059.pdf PDF (764.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-10-21
タイトル
言語 en
タイトル Perioperative therapy for non-small cell lung cancer - Current status and future perspective -
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 NAKATA, Masao

× NAKATA, Masao

WEKO 124909

en NAKATA, Masao

Search repository
NOJIMA, Yuji

× NOJIMA, Yuji

WEKO 124910

en NOJIMA, Yuji

Search repository
SAISHO, Shinsuke

× SAISHO, Shinsuke

WEKO 124911

en SAISHO, Shinsuke

Search repository
KUROSAKI, Takeshi

× KUROSAKI, Takeshi

WEKO 124912

en KUROSAKI, Takeshi

Search repository
SHIMIZU, Katsuhiko

× SHIMIZU, Katsuhiko

WEKO 124913

en SHIMIZU, Katsuhiko

Search repository
著者所属(英)
en
Department of General Thoracic Surgery, Kawasaki Medical School
著者所属(英)
en
Department of General Thoracic Surgery, Kawasaki Medical School
著者所属(英)
en
Department of General Thoracic Surgery, Kawasaki Medical School
著者所属(英)
en
Department of General Thoracic Surgery, Kawasaki Medical School
著者所属(英)
en
Department of General Thoracic Surgery, Kawasaki Medical School
キーワード
言語 en
主題Scheme Other
主題 Non-small cell lung cancer
キーワード
言語 en
主題Scheme Other
主題 Surgery
キーワード
言語 en
主題Scheme Other
主題 Adjuvant therapy
キーワード
言語 en
主題Scheme Other
主題 Induction therapy
キーワード
言語 en
主題Scheme Other
主題 Immune checkpoint inhibitor
抄録(英)
en
Lung cancer is the leading cause of cancer-related death. Surgery has been playing a pivotal role in the treatments with curative intent for non-small cell lung cancer (NSCLC). However, the outcome after surgery alone remains unsatisfactory. During the last two decades, several attempts have been made to improve the postoperative outcome. Metaanalysis demonstrated that adjuvant cisplatin-based chemotherapy achieved 4-5% of benefit in the 5-year survival as compared to surgery alone. Preoperative induction chemotherapy also yielded a 5% improvement of the 5-year survival rate, showing a similar efficacy with adjuvant chemotherapy. Induction chemoradiotherapy enhanced local control, whereas it was not associated with any survival benefit. Recently, the development of new drugs, such as tyrosine kinase inhibitors and immune checkpoint inhibitors, represents a major treatment advance for patients with lung cancer. Several attempts have been made to apply these drugs to perioperative treatments.
 In this review, we sought to summarize the developments of perioperative therapy in the treatments of NSCLC, and discuss the future perspectives.
書誌情報 en : Kawasaki medical journal

巻 46, p. 59-72, 発行日 2020
出版者
出版者 Kawasaki Medical Society
ISSN
収録物識別子タイプ ISSN
収録物識別子 03850234
ISSN
収録物識別子タイプ ISSN
収録物識別子 24343404
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12685295
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12029005
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.11482/KMJ-E202046059
記事種別(英)
内容記述タイプ Other
内容記述 Review
医中誌ID
関連タイプ isIdenticalTo
識別子タイプ ICHUSHI
関連識別子 2022017986
関連サイト
識別子タイプ URI
関連識別子 https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2020en/KMJ-E202046059.pdf
関連名称 https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2020en/KMJ-E202046059.pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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