{"created":"2023-06-19T10:28:07.843597+00:00","id":294,"links":{},"metadata":{"_buckets":{"deposit":"69f7a0c2-6b11-4761-bbf7-4a5f0abaf41d"},"_deposit":{"created_by":31,"id":"294","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"294"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000294","sets":["1709617079800:37:91:365"]},"author_link":[],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1990","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"41","bibliographicPageStart":"33","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original Article","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1990en/16(1)33-41.1990.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-E16(1)33 ","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00710169","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0234","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2434-3404","subitem_source_identifier_type":"EISSN"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Biochemistry, Kawasaki Medical School"}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"Among four species of 6-O-methylglucose-containing lipopolysaccharides (MGLP)1,2) of Mycobacterium smegmatis, MGLP-I, which lacks succinyl residues, and MGLP-II, which contains one mol of succinyl residue per mol of MGLP, inhibited the activity of the acyl carrier protein (ACP)-dependent fatty acid elongation system (FAS-II)3) prepared from the same bacilli by ammonium sulfate precipitations and gel filtration of Sephacryl S-200. When the molar ratio of palmitoyl-CoA to MGLP-II was 1:1, the FAS-II activity was reduced to about 70% of the normal value. When it was 1:3, the activity was about 30%. MGLP-I, on the other hand, inhibited the activity of partially purified palmitoyl-CoA -ACP transacylase, which is one of enzymes of FAS-II. In addition, it also inhibited the activity of the acetyl-CoA-dependent fatty acid elongation system (FES-I)4) when the concentration of decanoyl-CoA used as the optimum primer was lower than its 2 Km value and the activity of the malonyl-CoA-dependent fatty acid elongation system (FES-II)5) when the concentration of stearoyl-CoA used as optimum primer was lower than 50μ-M (the standard concentration of the original assay). The physiological role of these lipopolysaccharides on the mycobacterial lipid metabolism was discussed. "}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SATO, Manabu","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00010211359.pdf","filesize":[{"value":"883.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00010211359.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/294/files/KJ00010211359.pdf"},"version_id":"d2f388df-82e3-49ac-8d1e-cbbf415f53d8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Inhibittion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"6-O-methylglucose-containing lipopolysaccharides","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Palmitoyl-CoA-ACP-transacylase","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of 6-O-Methylglucose-Containing Lipopolysaccharides on the Activity of Fatty Acid Elongation Systems in Mycobacterium Smeamatis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of 6-O-Methylglucose-Containing Lipopolysaccharides on the Activity of Fatty Acid Elongation Systems in Mycobacterium Smeamatis","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["365"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"294","relation_version_is_last":true,"title":["Effects of 6-O-Methylglucose-Containing Lipopolysaccharides on the Activity of Fatty Acid Elongation Systems in Mycobacterium Smeamatis"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-09-27T07:27:20.588323+00:00"}