{"created":"2023-06-19T10:30:52.160810+00:00","id":3019,"links":{},"metadata":{"_buckets":{"deposit":"98b1659d-80ce-41a8-93fe-87df8cb51bac"},"_deposit":{"created_by":3,"id":"3019","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3019"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00003019","sets":["1709617079800:37:801"]},"author_link":["131085","131088","131081","131086","131084","131083","131082","131087","131080"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"178","bibliographicPageStart":"167","bibliographicVolumeNumber":"47","bibliographic_titles":[{},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_10001_description_34":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Regular Article","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Kawasaki Medical Society"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-E202147167","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2021en/KMJ-E202147167.pdf","subitem_relation_type_select":"URI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12685295","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03850234","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"24343404","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_32":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology 1, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Koujin Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department of Urology, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Koujin Hospital"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology 1, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Pathology"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology 1, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology 1, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Obstetrics and Gynecology 1, Kawasaki Medical School"}]},"item_10001_textarea_5":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"　Pregnancy rate for in vitro fertilization (IVF) remains low, for which the quality of ovum may be a contributing factor. Hence, comprehensive analysis of cytokines in follicular fluid was performed to identify potential markers of ovum quality.\n　Ova from women undergoing IVF for male factors or unknown etiology, excluding those undergoing treatment for female factors, were selected for cytokine analysis. Comprehensive cytokine/chemokine analysis of follicular fluid was performed. Next, enzyme-linked immunosorbent assay (ELISA) for quantifying interleukin (IL)-4, IL-17A, and IL-1ra levels in the serum and follicular fluid of 142 randomly selected patients was conducted.\n　The comprehensive analysis revealed significant differences in the levels of IL-4, IL-17A, and IL-1ra in the follicular fluid from all ovum grades. The cytokine levels in serum revealed a significant difference in IL-17A levels between women whose ova developed into blastocysts and women whose ova did not. However, no significant differences were found in the cytokine levels of follicular fluid.\n　No significant difference were found between the follicular fluid of women whose ova developed into blastocysts and those whose ova did not; however, serum IL-17A levels significantly differed. Therefore, serum IL-17A levels may be the marker of ovum quality."}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MATSUMOTO, Keiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUYAMA, Takehiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OHIRA, Shin","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKAZAWA, Rumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HAZAMA, Yukiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MORIYA, Takuya","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUMOTO, Ryo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKAMURA, Takafumi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHIMOYA, Koichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-01"}],"displaytype":"detail","filename":"KMJ-E202147167.pdf","filesize":[{"value":"996.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","url":"https://kwmed.repo.nii.ac.jp/record/3019/files/KMJ-E202147167.pdf"},"version_id":"ab429144-dca8-4f42-aa7f-73503a171e73"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Blastocyst","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cytokines","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Follicular fluid","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"IL-17A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"In vitro fertilization","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comprehensive analysis of cytokines in the follicular fluid and serum during in vitro fertilization and embryo transfer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comprehensive analysis of cytokines in the follicular fluid and serum during in vitro fertilization and embryo transfer","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"3","path":["801"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-04-01"},"publish_date":"2022-04-01","publish_status":"0","recid":"3019","relation_version_is_last":true,"title":["Comprehensive analysis of cytokines in the follicular fluid and serum during in vitro fertilization and embryo transfer"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T10:49:47.873270+00:00"}