{"created":"2023-06-19T10:30:55.533983+00:00","id":3079,"links":{},"metadata":{"_buckets":{"deposit":"54670209-b4d6-4c70-8637-a8a86c89e673"},"_deposit":{"created_by":29,"id":"3079","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"3079"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00003079","sets":["1709617079800:35:808"]},"author_link":["131502","131503","131504","131505","131506","131507","131508","131509","131510","131511","131512","131513","131514","131515","131516","131517","131518","131519"],"item_10001_alternative_title_1":{"attribute_name":"その他(別言語等)のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Temporal dispersion in vasculitic neuropathy: its microscopic ultrastructural findings","subitem_alternative_title_language":"en"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"86","bibliographicPageStart":"79","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_10001_description_33":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"症例報告","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10001_description_34":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Case Report","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"川崎医学会","subitem_publisher_language":"ja"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-J202248079","subitem_relation_type_select":"DOI"}}]},"item_10001_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2022/KMJ-J202248079.pdf","subitem_relation_type_select":"URI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN12940574","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2758-089X","subitem_source_identifier_type":"EISSN"}]},"item_10001_text_31":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学総合医療センター神経内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学病理学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学神経内科学"}]},"item_10001_text_32":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School General medical center"},{"subitem_text_language":"en","subitem_text_value":"Department of Pathology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Neurology Kawasaki Medical School"}]},"item_10001_textarea_5":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"　A previously healthy 35-year-old man developed abnormal sensation in the right sural and medial plantar nerve territory 2 years ago. The sensory impairment gradually spread to the left sural and medial plantar nerve regions, then bilateral ulnar nerve regions. Nerve conduction study showed temporal dispersion in the left tibial nerve. Sural nerve biopsy revealed necrotizing vasculitis with fibrinoid necrosis in the epineurium. Toluidine blue staining of Epon-embedded tissue showed significant loss of myelinated nerve fibers without demyelination, even in the teased nerve fiber preparations. Electron microscopy showed immature regenerated nerve fibers with thin myelin sheaths. Even including 24 reported cases of vasculitic neuropathy with either conduction block, pseudo-conduction block, or temporal dispersion, this is the first case examined by electron microscopy. Herein, we discuss the ultrastructural background of“temporal dispersion”in vasculitic neuropathy."}]},"item_10001_textarea_6":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"　症例は35歳男性．32歳のときに右腓腹神経・足底神経支配領域の異常感覚で発症し，その後，左腓腹神経・足底神経領域，両側尺骨神経領域に感覚障害が拡大した．神経伝導検査では，左脛骨神経複合筋活電位において，時間的分散の所見が認められた．腓腹神経生検では，神経上膜にフィブリノイド壊死を伴う壊死性血管炎を認めた．エポン包埋トルイジン青染色では、有髄神経線維の脱落が著明であり，髄鞘の薄い再生軸索が認められた．電子顕微鏡による観察では，脱髄は認められず，軸索の再生が認められたが，髄鞘再生に乏しい thin myelin が特徴的であった．神経伝導検査で，伝導ブロックや時間的分散といった脱髄を疑う所見を呈する血管炎性ニューロパチーについて24例の報告があるが，これまで電子顕微鏡による観察はされていない．血管炎性ニューロパチーによって惹起される時間的分散の出現機序について，微細構造所見を基に考察する．"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"白河, 俊一","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131502","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大澤, 裕","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131503","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"黒川, 勝己","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131504","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西村, 広健","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131505","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"久徳, 弓子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131506","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"逸見, 祥司","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131507","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"村上, 龍文","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131508","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"三原, 雅史","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131509","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"砂田, 芳秀","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"131510","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SHIRAKAWA, Shunichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131511","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OSAWA, Yutaka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131512","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KUROKAWA, Katsumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131513","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"NISHIMURA, Hirotake","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131514","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"KUTOKU, Yumiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131515","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"HENMI, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131516","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MURAKAMI, Tatsufumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131517","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MIHARA, Masahito","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131518","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SUNADA, Yoshihide","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"131519","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-10"}],"displaytype":"detail","filename":"KMJ-J202248079.pdf","filesize":[{"value":"3.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PDF","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/3079/files/KMJ-J202248079.pdf"},"version_id":"a3d90b60-48a4-4618-80cd-102c0ec090a9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"血管炎性ニューロパチー","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"時間的分散","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Vasculitic neuropathy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Temporal dispersion","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"血管炎性ニューロパチーにおける時間的分散（temporal dispersion） : 電子顕微鏡的微細構造解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"血管炎性ニューロパチーにおける時間的分散（temporal dispersion） : 電子顕微鏡的微細構造解析","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"29","path":["808"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-10"},"publish_date":"2023-03-10","publish_status":"0","recid":"3079","relation_version_is_last":true,"title":["血管炎性ニューロパチーにおける時間的分散（temporal dispersion） : 電子顕微鏡的微細構造解析"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2024-08-15T06:42:09.841023+00:00"}