| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
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タイトル |
A New Dissolution Effect of DMO on Human Pancreatic Stone : In vitro Study |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
HINO, Kazunari
TAKATORI, Keiko
YAMAMOTO, Ryosuke
IDEGUCHI, Seiji
OHMOTO, Kenji
OHUMI, Tsuneyo
YAMAMOTO, Shinichiro
HIRANO, Yutaka
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| 著者所属(英) |
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en |
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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en |
|
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
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en |
|
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
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en |
|
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
|
主題 |
Pancreatic stone dissolution therapy |
| キーワード |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Dimethadione(DMO) |
| キーワード |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Calcium carbonate |
| 記事種別(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Original Article |
|
言語 |
en |
| 抄録(英) |
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en |
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In this study, we examined the dissolution effect of dimethadione (DMO) on pancreatic stones, when kept at 37°C in a DMO 0.05 M NaHC03 saline solution which was replaced once a week, were partially dissolved during a 12-week period. The decreasing stone weight ratios were 38% (1.0 g/1 DMO), 41% (0.5 g/1), 7% (0.1 g/1), and 2% (control). The DMO solution induced a concentration-dependent increase in the solubility of the pancreatic stones associated with a concentration-dependent fall in the solution pH. The eluted calcium concentration in the solution was measured after one week's incubation, and then the decrease in stone weight in theory was calculated. The decrease in stone weight in practice, however, was more than the calculated weight in theory. To determine the reason for this discrepancy, we examined the solution microscopically for sediment and found amorphous substances indicating a concentration-dependent increase in the amount of sediment. These substances resembled artificially broken pancreatic stones and they were dissolved by bubbles following the addition of acetic acid. This phenomenon suggests that these substances and pancreatic stones consist of CaC03. Therefore, it appears DMO has the potency not only to dissolve CaCO3, but also to break pancreatic stones into small pieces. |
| 書誌情報 |
en : Kawasaki medical journal
巻 17,
号 1-4,
p. 15-22,
発行日 1991
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| URL |
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|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1991en/17(1.2.3.4)15-22.1991.pdf |
|
識別子タイプ |
URI |
| DOI |
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識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.11482/KMJ-E17(1.2.3.4)15-22.1991 |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0385-0234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12029005 |
| 著者版フラグ |
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出版タイプ |
VoR |
KJ00010206939.pdf (2.5 MB)
