{"created":"2023-06-19T10:28:10.030232+00:00","id":322,"links":{},"metadata":{"_buckets":{"deposit":"a952d5d3-e0e8-4e1d-88a5-14c2a98ae5f3"},"_deposit":{"created_by":31,"id":"322","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"322"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000322","sets":["1709617079800:37:107:369"]},"author_link":["126427","126428","126429","126430","126431","126432","126433","126434"],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"28","bibliographicPageStart":"23","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"記事種別(英)","attribute_value_mlt":[{"subitem_description":"Original Article","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1991en/17(1.2.3.4)23-28.1991.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-E17(1.2.3.4)23-28.1991","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00710169","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0234","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2434-3404","subitem_source_identifier_type":"EISSN"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Division of Gastroenterology 1, Department of Medicine, Kawasaki Medical School"}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"Serum 7S collagen was measured in 100 patients with Hepatitis C virus (HCV)-Ab positive chronic liver disease using RIA kit (7S-RIA : Japan DPC Corporation). The serum levels of 7S collagen were significantly higher in all types of liver diseases than those in 20 healthy controls (3.9±0.4 ng/ml). The 7S collagen level was 8.4±3.6 ng/ml (n = 30) in chronic hepatitis (CH), 14.4±8.1 ng/ml (n = 30) in liver cirrhosis (LC), 14.5 ±8.6 ng/ml (n=40) in hepatocellular carcinoma (HCC). In chronic hepatitis, chronic active hepatitis had a mean 7S collagen value of 9.8±3.8 ng/ml (n=19), while that of chronic inactive hepatitis was 6.1±1.8 ng/ml (n=11). In decompensated liver cirrhosis, the 7S collagen value was 17.6±9.2 ng/ml (n=17), whereas that of compensated LC was 10.2±3.1 ng/ml (n=13). In HCC, 7S collagen was examined according to the size of the tumor. In HCC with a diameter of less than 3 cm, the value was 11.0±4.2 ng/ml (n = 5). In 3 to 5 cm lesions, it was 12.5±5.8 ng/ml (n=16) and those more than 5 cm in diameter, it was 17.1 ±10.8 ng/ml (n=19). Although there were no significant differences according to size, there was a tendency for the level of 7S collagen to increase with the size of the tumor. The HCV-Ab titer and 7S collagen level showed no significant correlation. Measurement of serum 7S collagen may be useful for the evaluation of the degree of progression of LC and HCC. "}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"TAKATORI, Keiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Shinichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YAMAMOTO, Ryosuke","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"IDEGUCHI, Seiji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OHMOTO, Kenji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OHUMI, Tsuneyo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HINO, Kazunari","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HIRANO, Yutaka","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00010210139.pdf","filesize":[{"value":"465.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00010210139.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/322/files/KJ00010210139.pdf"},"version_id":"e33fb554-4c22-4757-819b-6f42a0c68ebc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Serum 7S collagen","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HCV-Ab positive chronic liver diseases","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Serum Levels of 7S Collagen in HCV-Ab Positive Chronic Liver Diseases","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serum Levels of 7S Collagen in HCV-Ab Positive Chronic Liver Diseases","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["369"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"322","relation_version_is_last":true,"title":["Serum Levels of 7S Collagen in HCV-Ab Positive Chronic Liver Diseases"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-09-28T00:19:45.670154+00:00"}