{"created":"2023-06-19T10:28:20.780009+00:00","id":495,"links":{},"metadata":{"_buckets":{"deposit":"0e68bd9f-5af2-495e-8cd6-438232c197a6"},"_deposit":{"created_by":31,"id":"495","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"495"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000495","sets":["1709617079800:37:140:406"]},"author_link":[],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3･4","bibliographicPageEnd":"97","bibliographicPageStart":"91","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2001en/27(3.4)91-97.2001.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ27(3.4)91-97.2001.pdf","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00710169","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0234","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2434-3404","subitem_source_identifier_type":"EISSN"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Biochemistry, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Nutrition, Faculty of Medical Professions, Kawasaki University of Medical Welfare"},{"subitem_text_language":"en","subitem_text_value":"Pathology Research Division, Department of Medical Research (Lower Myanmar)"}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"During the making of a precise molecular diagnosis of blood from transfusion dependent anemic patients in the Union of Myanmar by the PCR-sequencing technique, we encountered two Myanmar children (My-194 and My-201) with a rare abnormal hemoglobin, Hb Monroe [β30(B12)Arg→Thr], which causes β^0-thalassemia due to missplicing in the course of mRNA processing. One of the children, My-194, was a compound heterozygote for Hb Monroe and a thalassemia mutation of βIVS I-5 G→C, who had a condition of severeβ^+-thalassemia resembling a β^0-thalassemia, while the other, My-201, a homozygote for Hb Monroe. However, Hb analyses of My-194 with IEF and DEAE-HPLC revealed a normal pattern, suggesting that it may be due to blood transfusion. Hb analyses of My-201 showed the presence of Hb A to be about 0%, with Hb F being the main Hb component, suggesting that in this case Hb F instead of Hb A may be produced as the main Hb."}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HARANO, Teruo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"HARANO, Keiko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"WIN, Ne","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00001983886.pdf","filesize":[{"value":"456.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00001983886.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/495/files/KJ00001983886.pdf"},"version_id":"64056bca-6a6f-4594-8912-16db78cda110"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"PCR-sequencing","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Hb analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Union of Myanmar","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Hb Monroe","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"β-thalassemia","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Rare Super-Unstable Hemoglobin Variant, Hb Monroe [β30(B12)Arg→Thr], Found in Two Myanmar Children","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Rare Super-Unstable Hemoglobin Variant, Hb Monroe [β30(B12)Arg→Thr], Found in Two Myanmar Children","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["406"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"495","relation_version_is_last":true,"title":["A Rare Super-Unstable Hemoglobin Variant, Hb Monroe [β30(B12)Arg→Thr], Found in Two Myanmar Children"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-10-07T02:03:29.840176+00:00"}