{"created":"2023-06-19T10:28:23.123003+00:00","id":531,"links":{},"metadata":{"_buckets":{"deposit":"3a04b15a-4f54-4fbd-ac46-920c0d9b2a56"},"_deposit":{"created_by":31,"id":"531","owners":[31],"pid":{"revision_id":0,"type":"depid","value":"531"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000531","sets":["1709617079800:37:148:411"]},"author_link":["125612","125613","125614","125615"],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1･2","bibliographicPageEnd":"43","bibliographicPageStart":"33","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2003en/29(1.2)33-43.2003.PDF.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-E29(1/2)033 ","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_1":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00710169","subitem_source_identifier_type":"NCID"},{"subitem_source_identifier":"AA12029005","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0385-0234","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"2434-3404","subitem_source_identifier_type":"EISSN"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Hygiene, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hygiene, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Hygiene, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medical Welfare Environmental Design, Kawasaki University of Medical Welfare"}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"The past several years, we have been investigating immunological aspects of silicosis focusing on Fas-mediated apoptosis. We found elevated serum level of soluble Fas (sFas) molecule, higher gene expression of sFas and decoy receptor 3 (DcR3) genes in peripheral blood mononuclear cells (PBMC) than healthy volunteers, and various alternatively spliced Fas transcripts in PBMC. The factor analysis using these results indicated that there were a small number of patients who developed immunological diseases without presenting with respiratory disorders. In addition, we discuss the mechanism involved in the development of autoimmune disorders found in silicosis patients."}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"OTSUKI, Takemi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKATA, Akiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"HYODOH, Fuminori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UEKI, Ayako","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00000010579.pdf","filesize":[{"value":"946.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000010579.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/531/files/KJ00000010579.pdf"},"version_id":"28e00ee8-277b-4a96-ac2b-bdc20714bd64"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"silicosisapoptosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Fas","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"autoimmune diseases","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Review of Regulation for the Fas-mediated Apoptotic Pathway in Silicosis Patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Review of Regulation for the Fas-mediated Apoptotic Pathway in Silicosis Patients","subitem_title_language":"en"}]},"item_type_id":"3","owner":"31","path":["411"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"531","relation_version_is_last":true,"title":["Review of Regulation for the Fas-mediated Apoptotic Pathway in Silicosis Patients"],"weko_creator_id":"31","weko_shared_id":-1},"updated":"2023-10-10T00:33:48.904256+00:00"}