{"created":"2023-06-19T10:28:28.608463+00:00","id":615,"links":{},"metadata":{"_buckets":{"deposit":"dec5ff2e-6d74-4365-a3a7-fa0675555f75"},"_deposit":{"created_by":25,"id":"615","owners":[25],"pid":{"revision_id":0,"type":"depid","value":"615"},"status":"published"},"_oai":{"id":"oai:kwmed.repo.nii.ac.jp:00000615","sets":["1709617079800:35:186:431"]},"author_link":["120188","120189","120190","120191","120192","120193","120194","120195","120196","120197","120198","120199","120200","120201","120202","120203","120204","120205","120206","120207"],"item_1694495855422":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_type":"VoR"}]},"item_3_biblio_info_12":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1987","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"241","bibliographicPageStart":"234","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"川崎医学会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Kawasaki medical journal","bibliographic_titleLang":"en"}]}]},"item_3_description_8":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_description":"原著","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_3_identifier_14":{"attribute_name":"URL","attribute_value_mlt":[{"subitem_identifier_type":"URI","subitem_identifier_uri":"http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1987/KMJ13(3)234-241.1987.pdf"}]},"item_3_relation_20":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.11482/KMJ-J13(3)234 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(川崎医科大学附属川崎病院内科(現))"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院病理"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院内科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院外科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院外科"},{"subitem_text_language":"ja","subitem_text_value":"川崎医科大学附属川崎病院外科"}]},"item_3_text_7":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Department of Pathology, Kawasaki Hospital, Kawasaki Medical School (Department of Medicine, Kawasaki Hospital, Kawasaki Medical School)"},{"subitem_text_language":"en","subitem_text_value":"Department of Pathology, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Medicine, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Surgery, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Surgery, Kawasaki Hospital, Kawasaki Medical School"},{"subitem_text_language":"en","subitem_text_value":"Department of Surgery, Kawasaki Hospital, Kawasaki Medical School"}]},"item_3_textarea_10":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_textarea_language":"ja","subitem_textarea_value":"胆嚢粘膜の腸上皮化生が胆嚢癌の組織発生にどのように関与しているかを探る目的で,胆嚢前癌性病変および胆嚢癌組織内にみられた化生性変化の種類と頻度を組織学的に検討した.対象として腺腫8例,異型上皮7例,過形成性ポリープ20例,粘膜癌11例および進行癌37例の計83例を用いた.その結果,異型上皮では杯細胞,粘液腺および内分泌細胞が60～80%の頻度でみられ,また過形成性ポリープでも粘液腺,杯細胞,内分泌細胞およびパネート細胞がおのおの10～100%の頻度で認められた.しかし腺腫では杯細胞のみが25%にみられたにすぎなかった.また粘膜癌では杯細胞と内分泌細胞が22～36%で,進行癌では同様の細胞が8～16%で認められた.以上より,胆嚢粘膜の腸上皮化生は,種々の化生性変化を高率に伴う異型上皮や過形成性ポリープから癌化する場合に重要な役割を演じ,化生性変化を伴うことが少ない腺腫からの癌化にはあまり関与しないものと推定した."}]},"item_3_textarea_11":{"attribute_name":"抄録(英)","attribute_value_mlt":[{"subitem_textarea_language":"en","subitem_textarea_value":"In order to study the relationship between mucosal metaplastic changes and cancer histogenesis in the gallbladder, precancerous lesions and carcinomas were investigated histologically for frequency and the variety of intestinal metaplasia in them. The materials included 8 cases of adenoma, 7 cases of dysplasia, 20 cases of hyperplastic polyp, 11 cases of mucosal carcinoma and 37 cases of advanced carcinoma. Goblet cells, mucous glands and endocrine cells were detected in 60-80% of cases with dysplasia and 10-100% of cases with hyperplastic polyp. However, adenoma only displayed goblet cells in 25% of cases. In cases with carcinoma, goblet cells and endocrine cells were present in 22-36% of mucosal carcinomas and 8-16% of advanced carcinomas, all of which were well differentiated adenocarcinomas. These results seem to indicate that intestinal metaplasia play an important role in malignant changes from dysplasia and hyperplastic polyp rather than adenoma."}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 博道","creatorNameLang":"ja"},{"creatorName":"サトウ, ヒロミチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"伊藤, 慈秀","creatorNameLang":"ja"},{"creatorName":"イトウ, ジシュウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加藤, 啓一郎","creatorNameLang":"ja"},{"creatorName":"カトウ, ケイイチロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"末宗, 康宏","creatorNameLang":"ja"},{"creatorName":"スエムネ, ヤスヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"釈舎, 龍三","creatorNameLang":"ja"},{"creatorName":"トキヤ, リュウゾウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大村, 晃一","creatorNameLang":"ja"},{"creatorName":"オオムラ, コウイチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小林, 敏成","creatorNameLang":"ja"},{"creatorName":"コバヤシ, トシナリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田原, 昌人","creatorNameLang":"ja"},{"creatorName":"タハラ, マサト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"光野, 正人","creatorNameLang":"ja"},{"creatorName":"コウノ, マサト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"吉岡, 一由","creatorNameLang":"ja"},{"creatorName":"ヨシオカ, カズヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Hiromichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Jishu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kato, Keiichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suemune, Yasuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tokiya, Ryuzo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omura, Koichi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kobayashi, Toshinari","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tahara, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kono, Masato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshioka, Kazuyoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-01-23"}],"displaytype":"detail","filename":"KJ00009816759.pdf","filesize":[{"value":"3.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00009816759.pdf","objectType":"fulltext","url":"https://kwmed.repo.nii.ac.jp/record/615/files/KJ00009816759.pdf"},"version_id":"34198db0-b809-4ea2-a9c0-e2e63686f476"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Intestinal metaplasia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Precancerous lesions and carcinomas","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Gallbladder","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"胆嚢前癌性病変および胆嚢癌組織における腸上皮化生の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胆嚢前癌性病変および胆嚢癌組織における腸上皮化生の検討","subitem_title_language":"ja"},{"subitem_title":"Metaplastic Changes in Precancerous Lesions and Carcinomas of the Gallbladder","subitem_title_language":"en"}]},"item_type_id":"3","owner":"25","path":["431"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-01-23"},"publish_date":"2017-01-23","publish_status":"0","recid":"615","relation_version_is_last":true,"title":["胆嚢前癌性病変および胆嚢癌組織における腸上皮化生の検討"],"weko_creator_id":"25","weko_shared_id":-1},"updated":"2023-10-06T04:23:00.302075+00:00"}