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Very Long Chain Fatty Acid Contents in the Sera of Patients with Adrenoleukodystrophy and Adrenomyeloneuropathy Measured by Selected-Ion-Monitoring Gas Chromatography/Mass Spectrometry
https://kwmed.repo.nii.ac.jp/records/323
https://kwmed.repo.nii.ac.jp/records/32306253494-b170-45ce-9e99-23b2a1161053
名前 / ファイル | ライセンス | アクション |
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KJ00010210179.pdf (729.8 kB)
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-01-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Very Long Chain Fatty Acid Contents in the Sera of Patients with Adrenoleukodystrophy and Adrenomyeloneuropathy Measured by Selected-Ion-Monitoring Gas Chromatography/Mass Spectrometry | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
KAWAI, Kingo
× KAWAI, Kingo |
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著者所属(英) | ||||||
en | ||||||
Department of Neurology, Kawasaki Medical School | ||||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Saturated very long chain fatty acids | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Adrenoleukodystrophy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Adrenomyeloneuropathy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Selected-ion-monitoring gas chromatography/mass spectrometry | |||||
記事種別(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Original Article | |||||
言語 | en | |||||
抄録(英) | ||||||
en | ||||||
Saturated very long chain fatty acid (VLCFAs, C22:0 - C28 :0) contents in the sera of 9 adrenoleukodystrophy (ALD) patients, 4 adrenomyeloneuropathy (AMN) patients, and 11 age-matched normal controls were determined by gas chromatography (GC), GC/mass spectrometry (MS) and selected-ion-monitoring (SIM)-GC/MS. The following results were obtained. The C22:0 contents of the ALD and AMN groups were not significantly different from those of the control group. However, the C24: 0 contents of the ALD and AMN groups were respectively, 1.9 and 1.5 times higher than control, and the C26:0 contents of these groups measured by SIM-GC/MS were 7.7 and 7.8 times higher than the control. These contents were about half of those measured by GC alone. The C28 :0 content of human sera could be measured for the first time in this study using SIM-GC/MS. The order of the increasing rate of the individual VLCFAs of ALD and AMN as compared that with the control was as follows, C26 : 0 > C28 : 0 > C24 : 0. | ||||||
書誌情報 |
en : Kawasaki medical journal 巻 17, 号 1-4, p. 29-36, 発行日 1991 |
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URL | ||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1991en/17(1.2.3.4)29-36.1991.pdf | |||||
識別子タイプ | URI | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/KMJ-E17(1.2.3.4)29-36.1991 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0385-0234 | |||||
ISSN | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2434-3404 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00710169 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12029005 | |||||
著者版フラグ | ||||||
出版タイプ | VoR |