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Further Studies on the Postmortem Changes of Red Blood Cells
https://kwmed.repo.nii.ac.jp/records/105
https://kwmed.repo.nii.ac.jp/records/105384f8651-2edc-41a6-ad4e-b67ffef121de
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00010224679.pdf (881.2 kB)
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| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-01-23 | |||||||
| タイトル | ||||||||
| タイトル | Further Studies on the Postmortem Changes of Red Blood Cells | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
TOMITA, Masafumi
× TOMITA, Masafumi
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department of Legal Medicine, Kawasaki Medical School | ||||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | osmotic fragility | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | postmortem changes | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | red cell membrane | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | rat | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original Article | |||||||
| 言語 | en | |||||||
| 抄録(英) | ||||||||
| en | ||||||||
| Postmortem changes in membrane components of red cells were investigated. The membrane components examined were sialic acid, protein subunits and lipids. Under ether anesthesia, rats were killed by stabbing in the breast to induce hemorrhage, after which blood was drawn from thorax. The observation period was limited to 18 hours after death, during which time changes in osmotic fragility and red cell shape are clearly observed. The quantity of sialic acid declined with the passage of time during this early postmortem period. The value at 18 hours was about 75 per cent of that in normal cells. The subunit patterns obtained by PAGE of membrane proteins of cells 18 hours after death were similar to those of normal red cells. In spite of the decrease in sialic acid content, PAS staining yielded no difference between normal and 18-hour-postmortem red cells, and it was thought that membrane proteins did not change markedly during this early postmortem period. It was found that changes in lipid composition happened within 3 hours of death, and fragments were observed. The decrease in free cholesterol was most remarkable, and at 18 hours after death the cholesterol level fell to about 75 per cent of that of normal red cells. The ratio of free cholesterol to total phospholipid decreased from 0.44 to 0.36. These results suggest that a significant decrease in free cholesterol in red cell membrane may hold the key as to why changes in osmotic fragility and red cell shape occur during the early postmortem period. | ||||||||
| 書誌情報 |
en : Kawasaki medical journal 巻 10, 号 1, p. 27-35, 発行日 1984 |
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| URL | ||||||||
| 識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1984en/10(1)27-35.1984.pdf | |||||||
| 識別子タイプ | URI | |||||||
| DOI | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.11482/KMJ-E10(1)27 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 0385-0234 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 2434-3404 | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00710169 | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA12029005 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
