| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
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タイトル |
Prostaglandin E Production in Bone Lesion of Transplanted VX-2 Tumor in Rabbits |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
OTSUKA, Nobuaki
MORITA, Rikushi
YONEDA, Masaya
MURANAKA, Akira
YAMAGIMOTO, Shinichi
TOMOMITSU, Tatsushi
NISHISHITA, Soichi
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| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
|
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en |
|
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Division of Nuclear Medicine, Department of Radiology, Kawasaki Medical School |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
VX-2 tumor |
| キーワード |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
prostaglandin E |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
bone lesion |
| 記事種別(英) |
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内容記述タイプ |
Other |
|
内容記述 |
Original Article |
|
言語 |
en |
| 抄録(英) |
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|
en |
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The correlation between prostaglandin E (PGE) and advance of tumor metastasis was investigated in normal and VX-2 bearing rabbits. PGE in plasma of normal rabbits was 486.2± 185.7 pg/ml (n=86). In rabbits with VX-2 dispersed into heart cavity, the circulating PGE levels increased when tumor cells lodged and proliferated in the lymphnode, lung, liver and bone marrow. However, the plasma levels of PGE in the rabbits with bone involvement were significantly higher than those without bone involvement. This data indicates that PGE produced at the bone lesion may mediate the osteoclastic bone resorption and destroy bone. In vitro studies revealed that PGE level increased in the culture medium of VX-2 tumor cells, while an appreciable increase was not noted in HeLa S3. |
| 書誌情報 |
en : Kawasaki medical journal
巻 10,
号 1,
p. 45-48,
発行日 1984
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| URL |
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|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1984en/10(1)45-48.1984.pdf |
|
識別子タイプ |
URI |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.11482/KMJ-E10(1)45 |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0385-0234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
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出版タイプ |
VoR |
KJ00010224759.pdf (420.4 kB)
