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We administered 3g of Meropenem daily to 20 patients with severe pneumonia: 8 communityacquired pneumonia patients, 9 nursing and healthcare-associated pneumonia patients, and 3 hospital-acquired pneumonia patients. It was effective in 15 of the 20 patients (75%): 8 of 8 community-acquired pneumonia patients (100%), 6 of 9 nursing and healthcare-associated pneumonia patients (66.6%), and 1 of 3 hospital-acquired pneumonia patients (33.3%). Bacteriologically, 9 of a total of 10 strains (90%) were eradicated: 4 of 4 Streptococcus pneumoniae strains, 2 of 2 methicillin-sensitive Staphlococcus aureus strains, 1 of 2 Enterococcus faecalis strains, 1 of 1 Klebsiella pneumoniae strain, and 1 of 1 Escherichia coli strain. Hepatic dysfunction was observed as a side effect in 8 patients (40%). Based on the above, administration of MEPM daily 3 g is extremely effective for community-acquired pneumonia, while it appears ineffective in many cases of nursing and healthcare-associated pneumonia or hospital-acquired pneumonia, and results in hepatic dysfunction at a high frequency."}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Okimoto, Niro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111638", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Katoh, Tadashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111639", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Hisataka", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111640", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hayashi, Toshikiyo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111641", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurihara, Takeyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111642", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyashita, Naoyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "111643", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-01-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00008397099.pdf", "filesize": [{"value": "221.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 221700.0, "url": {"label": "KJ00008397099.pdf", "url": "https://kwmed.repo.nii.ac.jp/record/1633/files/KJ00008397099.pdf"}, "version_id": "c9520859-8cb1-4593-ad1a-0e1255aa42ed"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Meropenem", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "3g,day administration", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Severe pneumonia", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Clinical effect of 3g/day administration of meropenem on severe pneumonia", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Clinical effect of 3g/day administration of meropenem on severe pneumonia", "subitem_title_language": "en"}]}, "item_type_id": "3", "owner": "3", "path": ["555"], "permalink_uri": "https://kwmed.repo.nii.ac.jp/records/1633", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-01-23"}, "publish_date": "2017-01-23", "publish_status": "0", "recid": "1633", "relation": {}, "relation_version_is_last": true, "title": ["Clinical effect of 3g/day administration of meropenem on severe pneumonia"], "weko_shared_id": -1}
Clinical effect of 3g/day administration of meropenem on severe pneumonia
https://kwmed.repo.nii.ac.jp/records/1633
https://kwmed.repo.nii.ac.jp/records/16339934866f-4f13-42d0-b4c2-d8dbbdaf96c3
名前 / ファイル | ライセンス | アクション |
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-01-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Clinical effect of 3g/day administration of meropenem on severe pneumonia | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Okimoto, Niro
× Okimoto, Niro× Katoh, Tadashi× Tanaka, Hisataka× Hayashi, Toshikiyo× Kurihara, Takeyuki× Miyashita, Naoyuki |
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著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
著者所属(英) | ||||||
en | ||||||
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School | ||||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Meropenem | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | 3g,day administration | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Severe pneumonia | |||||
記事種別(日) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 症例報告 | |||||
抄録(英) | ||||||
en | ||||||
We examined the clinical effect of Meropenem (MEPM) on severe pneumonia. We administered 3g of Meropenem daily to 20 patients with severe pneumonia: 8 communityacquired pneumonia patients, 9 nursing and healthcare-associated pneumonia patients, and 3 hospital-acquired pneumonia patients. It was effective in 15 of the 20 patients (75%): 8 of 8 community-acquired pneumonia patients (100%), 6 of 9 nursing and healthcare-associated pneumonia patients (66.6%), and 1 of 3 hospital-acquired pneumonia patients (33.3%). Bacteriologically, 9 of a total of 10 strains (90%) were eradicated: 4 of 4 Streptococcus pneumoniae strains, 2 of 2 methicillin-sensitive Staphlococcus aureus strains, 1 of 2 Enterococcus faecalis strains, 1 of 1 Klebsiella pneumoniae strain, and 1 of 1 Escherichia coli strain. Hepatic dysfunction was observed as a side effect in 8 patients (40%). Based on the above, administration of MEPM daily 3 g is extremely effective for community-acquired pneumonia, while it appears ineffective in many cases of nursing and healthcare-associated pneumonia or hospital-acquired pneumonia, and results in hepatic dysfunction at a high frequency. | ||||||
書誌情報 |
川崎医学会誌 en : Kawasaki medical journal 巻 39, 号 1, p. 43-47, 発行日 2013 |
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URL | ||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2013/KMJ31(1)43-47.2013.pdf | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2013/KMJ31(1)43-47.2013.pdf | |||||
識別子タイプ | URI | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.11482/2013/KMJ31(1)43-47.2013.pdf | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0386-5924 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2758-089X | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00045593 | |||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN12940574 |