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Hemoglobinopathies Due to Abnormal Functional Properties of Hemoglobin Molecule Part II. Stable Abnormal Hemoglobins with Increased Oxygen Affinity, Frequently Causing Polycythemia
https://kwmed.repo.nii.ac.jp/records/179
https://kwmed.repo.nii.ac.jp/records/179f3a3326c-e5b2-4a37-bf89-77f1e8bf050c
名前 / ファイル | ライセンス | アクション |
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2017-01-23 | |||||||||
タイトル | ||||||||||
タイトル | Hemoglobinopathies Due to Abnormal Functional Properties of Hemoglobin Molecule Part II. Stable Abnormal Hemoglobins with Increased Oxygen Affinity, Frequently Causing Polycythemia | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
Gulzar, A. Niazi
× Gulzar, A. Niazi
× Shibata, Susumu
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著者所属(英) | ||||||||||
en | ||||||||||
Department of Pathology, King Faisal University, College of Medicine and Medical Sciences | ||||||||||
著者所属(英) | ||||||||||
en | ||||||||||
Department of Medicine, Kawasaki Medical School | ||||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Hemoglobinopathies | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Hemoglobins with altered oxygen affinity | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Erythrocytosis | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Cyanosis | |||||||||
記事種別(英) | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Original Article | |||||||||
言語 | en | |||||||||
抄録(英) | ||||||||||
en | ||||||||||
In the first part of this review article stable abnormal hemoglobins of high oxygen affinity causing erythrocytosis were dealt with. About a half of them are due to mutation in the α1β2contact region of hemoglobin molecule, and the remaining half are mutational products originating in α1β1 contact, heme contact, 2,3 DPG binding site, etc. In the present paper, which forms the second part, stable variants of high oxygen affinity with mutations in the carboxy terminal segment, which cause either erythrocytosis or not, and the stable high oxygen affinity variants, the mutation of which involve α1β2 contact without association of erythrocytosis are described. In addition, instances of stable hemoglobin variants of increased oxygen affinity which do not lead to overt clinical symptoms are also discussed. | ||||||||||
書誌情報 |
en : Kawasaki medical journal 巻 12, 号 2, p. 67-76, 発行日 1986 |
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URL | ||||||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1986en/12(2)67-76.1986.pdf | |||||||||
識別子タイプ | URI | |||||||||
DOI | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.11482/KMJ-E12(2)67 | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 0385-0234 | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | EISSN | |||||||||
収録物識別子 | 2434-3404 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA00710169 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA12029005 | |||||||||
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出版タイプ | VoR |