| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2020-04-01 |
| タイトル |
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|
タイトル |
The role of Kyoto classification in the diagnosis of Helicobacter pylori infection and histologic gastritis among young subjects in Japan |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
SUEHIRO, Mitsuhiko
KAMADA, Tomoari
HARUMA, Ken
NAKAMURA, Jun
MANABE, Noriaki
MONOBE, Yasumasa
AKIYAMA, Takashi
MURAO, Takahisa
SHIOTANI Akiko
KAWAMOTO, Hirofumi
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| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Kawasaki Medical School, Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center |
| 著者所属(英) |
|
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言語 |
en |
|
値 |
Kawasaki Medical School, Department of Health Care Medicine, Kawasaki Medical School General Medical Center |
| 著者所属(英) |
|
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言語 |
en |
|
値 |
Kawasaki Medical School, Department of General Internal Medicine 2, Kawasaki Medical School General Medical Cente |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Kawasaki Medical School, Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Kawasaki Medical School, Department of Endoscopy and Ultrasound, Kawasaki Medical School General Medical Center |
| 著者所属(英) |
|
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言語 |
en |
|
値 |
Kawasaki Medical School, Department of Pathology, Kawasaki Medical School General Medical Center |
| 著者所属(英) |
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言語 |
en |
|
値 |
Department of Pathology, Kawasaki Medical School |
| 著者所属(英) |
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言語 |
en |
|
値 |
Department of Gastroenterology, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Department of Gastroenterology, Kawasaki Medical School |
| 著者所属(英) |
|
|
言語 |
en |
|
値 |
Kawasaki Medical School, Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Helicobacter pylori |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Kyoto classification; Gastritis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Young subjects |
| 抄録(英) |
|
|
言語 |
en |
|
値 |
BACKGROUND AND AIM: Helicobacter pylori (H. pylori) infection induces inflammation of the gastric mucosa and leads to erosions, gastro-duodenal mucosa atrophy, and intestinal metaplasia. The Kyoto classification diagnoses H. pylori infection via endoscopic findings. We aimed to clarify the role of the Kyoto classification in diagnosing H. pylori infection and histologic gastritis in young Japanese individuals.
METHODS: From1031 consecutive subjects aged ≤29 years who underwent esophagogastroduodenal endoscopy at our two hospitals from 2010 to 2017, 220 were selected for participation in the present study. Endoscopic biopsy specimens from the antrum and corpus were used to investigate H. pylori infection and histology. Endoscopic and histological interpretations were based on the Kyoto classification and updated Sydney System. H. pylori infection was confirmed by histology and Giemsa or Gimenez staining.
RESULTS: Endoscopic findings were normal in 103 cases. Atrophy was found in 56 cases; diffuse redness, in 45 cases; nodularity, in 38 cases; and mucosal swelling, in 34 cases. The infection rate was 30.9% (68/220). In total, 67 subjects with H. pylori -positive endoscopic findings and confirmed as H. pylori -positive had histologic gastritis of the antrum and corpus. In contrast, of 153 subjects with H. pylori -negative endoscopic findings only 1 was subsequently confirmed to be H. pylori positive. Among the 67 subjects with H. pylori -positive endoscopic findings, 23 (34.3%) presented with histological atrophic gastritis of the corpus and 6 (9.0%) with intestinal metaplasia.
CONCLUSIONS: Our findings show that H. pylori infection is strongly associated with endoscopic and histologic gastritis in young subjects and both H. pylori infection and histologic gastritis can be evaluated endoscopically based on the Kyoto classification. Furthermore, prompt H. pylori eradication may prevent gastric cancer development given the high prevalence of atrophic gastritis and intestinal metaplasia in young Japanese individuals. |
| 書誌情報 |
en : Kawasaki medical journal
巻 45,
p. 43-52,
発行日 2019
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| 出版者 |
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|
出版者 |
Kawasaki Medical Society |
| ISSN |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03850234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
24343404 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA12685295 |
| 書誌レコードID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| DOI |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.11482/KMJ-E201945043 |
| 記事種別(英) |
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|
内容記述 |
Regular Article |
|
言語 |
en |
| 医中誌ID |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
ICHUSHI |
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関連識別子 |
2020354377 |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2019en/KMJ-E201945043.pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
PDF (5.1 MB)
