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Role of Polysaccharides Extracted from Human-type Mycobacterium tuberculosis in the Collagen Proliferation and the Suppression of Cancer Growth : From a Point of Pathobiological View
https://kwmed.repo.nii.ac.jp/records/226
https://kwmed.repo.nii.ac.jp/records/2263f9fd0b6-4c02-4f51-a6df-2e30b9212fd8
名前 / ファイル | ライセンス | アクション |
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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公開日 | 2017-01-23 | |||||||
タイトル | ||||||||
タイトル | Role of Polysaccharides Extracted from Human-type Mycobacterium tuberculosis in the Collagen Proliferation and the Suppression of Cancer Growth : From a Point of Pathobiological View | |||||||
言語 | en | |||||||
言語 | ||||||||
言語 | eng | |||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
著者 |
KIMOTO, Tetsuo
× KIMOTO, Tetsuo
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著者所属(英) | ||||||||
en | ||||||||
Department of Pathology, Kawasaki Medical School | ||||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | human-type Mycobacterium tuberculosis | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | antitumor activity | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | collagenation | |||||||
キーワード | ||||||||
言語 | en | |||||||
主題Scheme | Other | |||||||
主題 | cancer envelopment | |||||||
記事種別(英) | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | Original Article | |||||||
言語 | en | |||||||
抄録(英) | ||||||||
en | ||||||||
The antitumor activity of Specific Substance Maruyama (SSM) consists of the activation and intensification of collagen proliferation in response to carcinoma. Experiments in vitro and in vivo (xenografts) indicated that SSM did not directly damage cancer cells, but that it did accelerate the proliferation of collagen fibers of the stroma. These collagen fibers enclosed the cancer cells, preventing their prolifer ation. Also, SSM remarkably accelerated the proliferation of collagen fibers under a specific or nonspecific immune condition. A basic activity of SSM thus appears to be the stimulation of the proliferation of collagen fibers in stroma invaded by cancer cells. The small blood vessels, blood capillaries, muscle fibers, and nerve fibers are partially composed of collagen. Furthermore, the biosynthesis of collagen seems to be accelerated by SSM in the carcinomatous necrotic lesions - a process that may also occur in fibroblasts, endothelial cells, and the extracellular matrices and cancer cells. | ||||||||
書誌情報 |
en : Kawasaki medical journal 巻 13, 号 4, p. 151-167, 発行日 1987 |
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URL | ||||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1987en/13(4)151-167.1987.pdf | |||||||
識別子タイプ | URI | |||||||
DOI | ||||||||
識別子タイプ | DOI | |||||||
関連識別子 | https://doi.org/10.11482/KMJ-E13(4)151 | |||||||
ISSN | ||||||||
収録物識別子タイプ | PISSN | |||||||
収録物識別子 | 0385-0234 | |||||||
ISSN | ||||||||
収録物識別子タイプ | EISSN | |||||||
収録物識別子 | 2434-3404 | |||||||
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収録物識別子タイプ | NCID | |||||||
収録物識別子 | AA00710169 | |||||||
雑誌書誌ID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AA12029005 | |||||||
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出版タイプ | VoR |