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  1. 川崎医学会機関誌
  2. Kawasaki Medical Journal
  3. Vol.47(2021)

Comparison of uterine artery waveforms during uterine contractions induced by oxytocin and prostaglandin

https://kwmed.repo.nii.ac.jp/records/3017
https://kwmed.repo.nii.ac.jp/records/3017
a452c8c2-38ff-4b21-9aee-5927ee680ddd
名前 / ファイル ライセンス アクション
KMJ-E202147151.pdf PDF (1.1 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2022-04-01
タイトル
タイトル Comparison of uterine artery waveforms during uterine contractions induced by oxytocin and prostaglandin
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 MATSUMOTO, Ryo

× MATSUMOTO, Ryo

en MATSUMOTO, Ryo

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NAKAI, Yuichiro

× NAKAI, Yuichiro

en NAKAI, Yuichiro

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SAITO, Wataru

× SAITO, Wataru

en SAITO, Wataru

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MATSUMOTO, Keiko

× MATSUMOTO, Keiko

en MATSUMOTO, Keiko

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HAZAMA, Yukiko

× HAZAMA, Yukiko

en HAZAMA, Yukiko

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SUGIHARA, Mika

× SUGIHARA, Mika

en SUGIHARA, Mika

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NAKAMURA, Takafumi

× NAKAMURA, Takafumi

en NAKAMURA, Takafumi

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SHIMOYA, Koichiro

× SHIMOYA, Koichiro

en SHIMOYA, Koichiro

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著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
著者所属(英)
言語 en
値 Department of Obstetrics and Gynecology 1, Kawasaki Medical School
キーワード
言語 en
主題Scheme Other
主題 Labor induction
キーワード
言語 en
主題Scheme Other
主題 Oxytocin
キーワード
言語 en
主題Scheme Other
主題 Prostaglandin
キーワード
言語 en
主題Scheme Other
主題 Uterine artery pulsatility index
キーワード
言語 en
主題Scheme Other
主題 Uterine artery resistance index
キーワード
言語 en
主題Scheme Other
主題 Uterine contraction
抄録(英)
言語 en
値 Background: Uterine artery waveforms are used as indicators of fetal growth restriction and pregnancy-induced hypertension; however, the findings of most reports were recorded when contractions were absent, leaving the dynamics during labor unclear. This present study aimed to investigate the effects of prostaglandin F2α (PGF2α) and oxytocin administrations on uterine artery resistance and pulsatility.
 Methods: This study was approved by the Ethics Committee of Kawasaki Medical School (3632) and was conducted in accordance with the ethical guidelines. The duration of the study was five years from the date of Ethics Committee approval.The participants included were 30 perinatal pregnant women who had no maternal or fetal complications admitted for delivery. The method used in inducing labor was randomly chosen (PGF2α and oxytocin were used in 15 cases each). Transabdominal ultrasonography was performed by a single experienced person to measure the uterine artery pulsatility index (PI) and resistance index (RI). The participants were divided into 3 subgroups based on cervical dilation (2-6 cm, 6-10 cm, and 10 cm to delivery). A univariate analysis was performed to evaluate the mean uterine artery PI and RI, and changes in labor stage were analyzed. The relationship between uterine artery RI and umbilical cord arterial pH was evaluated.
 Results: Vaginal delivery occurred in 15 and 11 cases in the oxytocin and PGF2α groups, respectively. Four babies with abnormal fetal heart rates were delivered via emergency cesarean section. There were no differences between the two groups concerning the duration of labor, bleeding during labor, placental weight, birth weight, or in cases of fetal asphyxia based on the Apgar score. No significant differences were observed in PI between the oxytocin and PGF2α groups in any of the three stages of labor(p > 0.05). In the oxytocin group, uterine arterial blood flow in terms of both RI and PI tended to be the highest at a cervical dilation of 6-10 cm. However, while a similar trend was observed for PI in the PGF2α group, RI was highest at a cervical dilation of ≥ 10 cm. No orrelations were found between RI and pH at any of the cervical dilation phases(p > 0.05).
 Conclusion: The results of our study showed that the type of labor-inducing agent had no effect on maternal circulation. The total infusion volume of PGF2α was larger than that of oxytocin; thus, it may be preferable to use oxytocin as a conventional induction method.
書誌情報 en : Kawasaki medical journal

巻 47, p. 151-158, 発行日 2021
出版者
出版者 Kawasaki Medical Society
ISSN
収録物識別子タイプ PISSN
収録物識別子 03850234
ISSN
収録物識別子タイプ EISSN
収録物識別子 24343404
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12685295
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA12029005
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.11482/KMJ-E202147151
記事種別(英)
内容記述 Regular Article
言語 en
関連サイト
識別子タイプ URI
関連識別子 https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2021en/KMJ-E202147151.pdf
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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