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Treatments and management for COVID-19
https://kwmed.repo.nii.ac.jp/records/3055
https://kwmed.repo.nii.ac.jp/records/30559a3a9571-940e-4964-b961-0894692885e4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PDF (705.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2023-03-10 | |||||||
| タイトル | ||||||||
| タイトル | Treatments and management for COVID-19 | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
OHASHI, Ichiro
× OHASHI, Ichiro
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| 著者所属(英) | ||||||||
| 言語 | en | |||||||
| 値 | Department of Anesthesiology & Intensive Care Medicine 3, Kawasaki Medical School | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | COVID-19 | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Treatment | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Cytokine storm | |||||||
| 抄録(英) | ||||||||
| 言語 | en | |||||||
| 値 | Humans have experienced three deadly pandemics in the twenty-first century which are associated with novel coronaviruses: severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and COVID-19. In this review, the treatments and management of COVID-19 were discussed. Cytokine storm mechanisms and therapy, there is no doubt that the elucidation of the mechanisms of the cytokine storm is an important key to conquer this pandemic. Many clinical trials have indicated the inhibitory effects of interleukin-6 (IL-6) for the treatment of COVID-19. Although no survival benefit was demonstrated in randomized, placebo-controlled studies, non-blinded, randomized studies have supported a survival benefit with IL-6 blockade. Inhibition of the excessive immune response in severe COVID-19 pneumonia undoubtedly improves the survival of patients, particularly through glucocorticoids given to those with oxygen requirements. From this point of view, timing of the administration of immunosuppressive or immunomodulatory agents is key issue. Prone position therapy was originally used to treat patients with severe acute respiratory distress syndrome (ARDS) resulting from pneumonia or sepsis. In the critically ill patients with severe pneumonitis, the prone position has been recommended as one of the most promising treatment options to improve mortality outcomes. Overall, this review covers, the epidemiology and the important aspects of the treatment and management against critically ill patients with COVID-19. | |||||||
| 書誌情報 |
en : Kawasaki medical journal 巻 48, p. 55-59, 発行日 2022 |
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| 出版者 | ||||||||
| 出版者 | Kawasaki Medical Society | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 24343404 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA12029005 | |||||||
| DOI | ||||||||
| 関連タイプ | isIdenticalTo | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.11482/KMJ-E202248055 | |||||||
| 記事種別(英) | ||||||||
| 内容記述 | Review | |||||||
| 言語 | en | |||||||
| 関連サイト | ||||||||
| 識別子タイプ | URI | |||||||
| 関連識別子 | https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2022en/KMJ-E202248055.pdf | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
