| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
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|
タイトル |
Hemoglobinopathies and Malaria Infection in Myanmar |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Aung, Myint Than
Harano, Teruo
Okada, Shigeru
|
| 著者所属(英) |
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|
en |
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Department of Biochemistry, Kawasaki Medical School |
| 著者所属(英) |
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|
en |
|
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Department of Biochemistry, Kawasaki Medical School |
| 著者所属(英) |
|
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|
en |
|
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Department of Clinical Nutrition, Faculty of Medical Professions, Kawasaki University of Medical Welfare |
| 著者所属(英) |
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|
en |
|
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Department of Pathological Research, Faculty of Medicine, Okayama University Graduate School of Medicine and Dentistry |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Malaria parasites |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Hemoglobin E |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
α-Thalassemia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
β-Thalassemia |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Polymerase chain reaction (PCR) |
| 抄録(英) |
|
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|
en |
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Screening for the incidences of hemoglobinopathies (Hb E, α-thalassemia (thal) and β-thal) and malaria infection was done in 131 healthy volunteers with no clinical symptoms in Shan State in Myanmar. The group consisted of 71 females and 60 males ranging in age from 16 to 46 years old. The analysis of hemoglobin was carried out using high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and DNA analysis was done by polymerase chain reaction (PCR)-electrophoresis. The incidences of carriers of Hb E, α-thal and β-thal were 17.6%, 7.6% and 0.8%, respectively. The thal genotypes observed were -α^<3.7>, which is an α-thal-2 mutation, and CD17A→T, which is β^0-thal mutation. Both are common mutations in Myanmar. There were only three (2.3%) carriers of two malaria parasites, Plasmodium falciparum (Pf) and Plasmodium vivax (Pv); namely one female carrier of Pf and two male carriers of Pv. Although it was suspected that the incidence of subjects infected with malaria would be high, there was comparatively small number of cases. This may be the reason why the blood sample collection from the volunteers was done during the dry season which is not the breeding season for malaria mosquitos. |
| 書誌情報 |
en : Kawasaki medical journal
巻 28,
号 1,
p. 9-15,
発行日 2002
|
| URL |
|
|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2002en/28(1)9-15.2002.pdf |
|
識別子タイプ |
URI |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.11482/KMJ28(1)9-15.2002.pdf |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0385-0234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
KJ00000010555.pdf (837.7 kB)
