| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
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|
タイトル |
Mononuclear Cell Clusters Observed in Pars Intermedius of Human Hypophysis |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
ISHIKAWA, Takaki
KOHARA, Kenji
MIYAISHI, Satoru
ISHIZU, Hideo
KAKU, Kohei
|
| 著者所属(英) |
|
|
|
en |
|
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Diabetes and Endocrine Division, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Diabetes and Endocrine Division, Department of Medicine, Kawasaki Medical School |
| 著者所属(英) |
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|
en |
|
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Department of Legal Medicine, Legal Medicine and Bioethics, Social and Environmental Sciences, Okayama University Graduate School of Medicine and Dentistry |
| 著者所属(英) |
|
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en |
|
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Department of Legal Medicine, Legal Medicine and Bioethics, Social and Environmental Sciences, Okayama University Graduate School of Medicine and Dentistry |
| 著者所属(英) |
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|
en |
|
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Diabetes and Endocrine Division, Department of Medicine, Kawasaki Medical School |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pars intermedius |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
lymphocytes |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
immunohistochemistry |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
B cells |
| 抄録(英) |
|
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|
en |
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We observed cell clusters morphologically resembling lymphocytes in the pars intermedius of human hypophyses, and investigated their immunohistochemical properties. These morphologically lymphocyte-like cells were not immunostained by any of the antibodies to hormones known to be present in the adenohypophysis or antidody to S-100 protein. However, immunostaining using antibodies to T cell membrane and B cell membrane showed that the cells were mainly stained by anti-B cell membrane antibodies. To investigate the stage of maturity of these B cell membrane-positive cells, we performed immunostaining using antibodies to IgG, 1gM and IgA, and obtained negative results for all three. However, the present study did not answer the questions of why these cells are found only in the pars intermedius, why they are mainly B cells, and what functions they possess. Although there is so far no evidence suggesting a relationship between this cell cluster and functions of the pars intermedius in the hypophysis, the pars intermedius in human is considered more degenerate compared to amphibians, birds and rodents, and is likely to possess some yet undiscovered functions. |
| 書誌情報 |
en : Kawasaki medical journal
巻 29,
号 1･2,
p. 17-24,
発行日 2003
|
| URL |
|
|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2003en/29(1.2)17-24.2003.PDF.pdf |
|
識別子タイプ |
URI |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.11482/KMJ29(1.2)17-24.2003.PDF.pdf |
| ISSN |
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収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0385-0234 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
KJ00000010577.pdf (1.4 MB)
