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The Changes of Collagen Synthesis Following the Active Arthus Reaction in the Guinea Pig Skin
https://kwmed.repo.nii.ac.jp/records/86
https://kwmed.repo.nii.ac.jp/records/86844867df-431c-4205-96b7-8d04a1e9abbd
名前 / ファイル | ライセンス | アクション |
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||||
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公開日 | 2017-01-23 | |||||||||
タイトル | ||||||||||
タイトル | The Changes of Collagen Synthesis Following the Active Arthus Reaction in the Guinea Pig Skin | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
資源タイプ | journal article | |||||||||
著者 |
HATANICHI, Atsushi
× HATANICHI, Atsushi
× UEKI, Hiroaki
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著者所属(英) | ||||||||||
en | ||||||||||
Department of Dermatology, Kawasaki Medical School | ||||||||||
著者所属(英) | ||||||||||
en | ||||||||||
Department of Dermatology, Kawasaki Medical School | ||||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Immune complex | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Active Arthus reaction | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Fibroblast | |||||||||
キーワード | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Collagen synthesis | |||||||||
記事種別(英) | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Original Article | |||||||||
言語 | en | |||||||||
抄録(英) | ||||||||||
en | ||||||||||
Active Arthus reactions were provoked by injecting 100 μg bovine serum albumin (BSA) into the skin of sensitized guinea pigs. Skin biopsy samples were taken 1, 4, 8, 24, 48, 72 and 120 hours after the provocation. Samples were labeled by intradermal injection of 10 μCi [3, 4- 3H]- proline for 1 hour and specific activity of radioactive proline per amount of protein was determined on 1 N NaOH extract of dermis as total protein synthesized. And the synthesized collagenous protein was measured as 3H-hydroxyproline by the method of Juva and Prockop. The results were compared with those obtained by the control injections of 100 μg BSA into the skin of non-sensitized guinea pigs. The synthesized total protein increased at 1, 4 and 8 hours, decreased at 24 hours and increased again at 72 hours. The time course of collagenous protein synthesis was nearly the same as that of total protein synthesis, however the synthesized collagenous protein was higher than the total protein synthesized 1 and 4 hours after the provocation. It was suggested that collagen synthesis increased in an active Arthus reaction up to 4 hours after the provocation. | ||||||||||
書誌情報 |
en : Kawasaki medical journal 巻 9, 号 3, p. 145-149, 発行日 1983 |
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URL | ||||||||||
識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1983en/9(3)145-149.1983.pdf | |||||||||
識別子タイプ | URI | |||||||||
DOI | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.11482/KMJ-E9(3)145 | |||||||||
ISSN | ||||||||||
収録物識別子タイプ | PISSN | |||||||||
収録物識別子 | 0385-0234 | |||||||||
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収録物識別子タイプ | EISSN | |||||||||
収録物識別子 | 2434-3404 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA00710169 | |||||||||
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収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AA12029005 | |||||||||
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出版タイプ | VoR |