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Effects of 6-O-Methylglucose-Containing Lipopolysaccharides on the Activity of Fatty Acid Elongation Systems in Mycobacterium Smeamatis
https://kwmed.repo.nii.ac.jp/records/294
https://kwmed.repo.nii.ac.jp/records/29470f701ae-5354-400e-a3a9-6cb91e457710
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00010211359.pdf (883.4 kB)
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| アイテムタイプ | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-01-23 | |||||||
| タイトル | ||||||||
| タイトル | Effects of 6-O-Methylglucose-Containing Lipopolysaccharides on the Activity of Fatty Acid Elongation Systems in Mycobacterium Smeamatis | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
SATO, Manabu
× SATO, Manabu
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department of Biochemistry, Kawasaki Medical School | ||||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Inhibittion | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | 6-O-methylglucose-containing lipopolysaccharides | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Palmitoyl-CoA-ACP-transacylase | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original Article | |||||||
| 言語 | en | |||||||
| 抄録(英) | ||||||||
| en | ||||||||
| Among four species of 6-O-methylglucose-containing lipopolysaccharides (MGLP)1,2) of Mycobacterium smegmatis, MGLP-I, which lacks succinyl residues, and MGLP-II, which contains one mol of succinyl residue per mol of MGLP, inhibited the activity of the acyl carrier protein (ACP)-dependent fatty acid elongation system (FAS-II)3) prepared from the same bacilli by ammonium sulfate precipitations and gel filtration of Sephacryl S-200. When the molar ratio of palmitoyl-CoA to MGLP-II was 1:1, the FAS-II activity was reduced to about 70% of the normal value. When it was 1:3, the activity was about 30%. MGLP-I, on the other hand, inhibited the activity of partially purified palmitoyl-CoA -ACP transacylase, which is one of enzymes of FAS-II. In addition, it also inhibited the activity of the acetyl-CoA-dependent fatty acid elongation system (FES-I)4) when the concentration of decanoyl-CoA used as the optimum primer was lower than its 2 Km value and the activity of the malonyl-CoA-dependent fatty acid elongation system (FES-II)5) when the concentration of stearoyl-CoA used as optimum primer was lower than 50μ-M (the standard concentration of the original assay). The physiological role of these lipopolysaccharides on the mycobacterial lipid metabolism was discussed. | ||||||||
| 書誌情報 |
en : Kawasaki medical journal 巻 16, 号 1, p. 33-41, 発行日 1990 |
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| URL | ||||||||
| 識別子 | http://igakkai.kms-igakkai.com/wp/wp-content/uploads/1990en/16(1)33-41.1990.pdf | |||||||
| 識別子タイプ | URI | |||||||
| DOI | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.11482/KMJ-E16(1)33 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 0385-0234 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 2434-3404 | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00710169 | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA12029005 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
