| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2022-04-01 |
| タイトル |
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|
タイトル |
Comprehensive analysis of cytokines in the follicular fluid and serum during in vitro fertilization and embryo transfer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
MATSUMOTO, Keiko
MATSUYAMA, Takehiko
OHIRA, Shin
NAKAZAWA, Rumi
HAZAMA, Yukiko
MORIYA, Takuya
MATSUMOTO, Ryo
NAKAMURA, Takafumi
SHIMOYA, Koichiro
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| 著者所属(英) |
|
|
|
en |
|
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Department of Obstetrics and Gynecology 1, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Koujin Hospital |
| 著者所属(英) |
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en |
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Department of Urology, Kawasaki Medical School |
| 著者所属(英) |
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en |
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Koujin Hospital |
| 著者所属(英) |
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|
en |
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Department of Obstetrics and Gynecology 1, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Department of Pathology |
| 著者所属(英) |
|
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|
en |
|
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Department of Obstetrics and Gynecology 1, Kawasaki Medical School |
| 著者所属(英) |
|
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en |
|
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Department of Obstetrics and Gynecology 1, Kawasaki Medical School |
| 著者所属(英) |
|
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en |
|
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Department of Obstetrics and Gynecology 1, Kawasaki Medical School |
| キーワード |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Blastocyst |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Cytokines |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Follicular fluid |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
IL-17A |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
In vitro fertilization |
| 抄録(英) |
|
|
|
en |
|
|
Pregnancy rate for in vitro fertilization (IVF) remains low, for which the quality of ovum may be a contributing factor. Hence, comprehensive analysis of cytokines in follicular fluid was performed to identify potential markers of ovum quality.
Ova from women undergoing IVF for male factors or unknown etiology, excluding those undergoing treatment for female factors, were selected for cytokine analysis. Comprehensive cytokine/chemokine analysis of follicular fluid was performed. Next, enzyme-linked immunosorbent assay (ELISA) for quantifying interleukin (IL)-4, IL-17A, and IL-1ra levels in the serum and follicular fluid of 142 randomly selected patients was conducted.
The comprehensive analysis revealed significant differences in the levels of IL-4, IL-17A, and IL-1ra in the follicular fluid from all ovum grades. The cytokine levels in serum revealed a significant difference in IL-17A levels between women whose ova developed into blastocysts and women whose ova did not. However, no significant differences were found in the cytokine levels of follicular fluid.
No significant difference were found between the follicular fluid of women whose ova developed into blastocysts and those whose ova did not; however, serum IL-17A levels significantly differed. Therefore, serum IL-17A levels may be the marker of ovum quality. |
| 書誌情報 |
en : Kawasaki medical journal
巻 47,
p. 167-178,
発行日 2021
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| 出版者 |
|
|
出版者 |
Kawasaki Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
03850234 |
| ISSN |
|
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
24343404 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12685295 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.11482/KMJ-E202147167 |
| 記事種別(英) |
|
|
内容記述 |
Regular Article |
|
言語 |
en |
| 関連サイト |
|
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|
識別子タイプ |
URI |
|
|
関連識別子 |
https://igakkai.kms-igakkai.com/wp/wp-content/uploads/2021en/KMJ-E202147167.pdf |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
PDF (996.0 kB)
