| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
|
|
タイトル |
Effect of Cetraxate, a Mucosal Protective Agent, on Gastric Mucosal Blood Flow and Gastric Clarithromycin Concentration in Nicotine-treated Rats |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
KAMADA, Tomoari
HARUMA, Ken
KUSUNOKI, Hiroaki
Mei, Qian Dong
SUGIU, Kuniaki
NAGASHIMA, Yuichi
KOGA, Hideki
TAKEDA, Masaharu
HONDA, Keisuke
FUJIMURA, Yoshinori
ITO, Masanori
TANAKA, Shinji
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| 著者所属(英) |
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|
|
en |
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Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
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en |
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Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
|
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
|
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
|
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
|
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
|
Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
|
|
en |
|
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Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School |
| 著者所属(英) |
|
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|
en |
|
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Department of Endoscopy, Hiroshima University Medical Hospital |
| 著者所属(英) |
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|
en |
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Department of Endoscopy, Hiroshima University Medical Hospital |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
gastric mucosal blood flow |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nicotine |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
cetraxate |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
clarithromycin |
| 抄録(英) |
|
|
|
en |
|
|
Our previous study demonstrated that combination treatment with cetraxate plus omeprazole, amoxicillin, and clarithromycin is effective for the eradication of Helicobacter pylon in smokers. To evaluate the effect of cetraxate on gastric mucosal blood flow (GMBF) and the gastric concentration of clarithromycin in nicotine-treated rats, 10 rats were divided into two groups given nicotine with or without cetraxate, and GMBF was measured by laser Doppler blood flowmetry. Another 36 rats were divided into three groups (control, nicotine, and nicotine + cetraxate). Clarithromycin was administered intraduodenally and nicotine was administered after 30 minutes, with cetraxate being given 30 minutes later. The gastric mucosal clarithromycin concentration was measured. After cetraxate administration, GMBF increased significantly in the nicotine + cetraxate group compared with the nicotine group (p<0.05). The mucosal clarithromycin concentration increased in the nicotine + cetraxate group compared with the nicotine group, but the difference was not significant. Our results indicate that cetraxate increased GMBF in nicotine-treated rats. |
| 書誌情報 |
en : Kawasaki medical journal
巻 28,
号 2･3･4,
p. 71-78,
発行日 2002
|
| URL |
|
|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2002en/28(2.3.4)71-78.2002.pdf |
|
識別子タイプ |
URI |
| DOI |
|
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.11482/KMJ28(2.3.4)71-78.2002.pdf |
| ISSN |
|
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0385-0234 |
| ISSN |
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
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|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
KJ00000010567.pdf (588.5 kB)
