| Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-01-23 |
| タイトル |
|
|
タイトル |
Review of Regulation for the Fas-mediated Apoptotic Pathway in Silicosis Patients |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
OTSUKI, Takemi
TAKATA, Akiko
HYODOH, Fuminori
UEKI, Ayako
|
| 著者所属(英) |
|
|
|
en |
|
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Department of Hygiene, Kawasaki Medical School |
| 著者所属(英) |
|
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en |
|
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Department of Hygiene, Kawasaki Medical School |
| 著者所属(英) |
|
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|
en |
|
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Department of Hygiene, Kawasaki Medical School |
| 著者所属(英) |
|
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|
en |
|
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Department of Medical Welfare Environmental Design, Kawasaki University of Medical Welfare |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
silicosisapoptosis |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Fas |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
autoimmune diseases |
| 抄録(英) |
|
|
|
en |
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The past several years, we have been investigating immunological aspects of silicosis focusing on Fas-mediated apoptosis. We found elevated serum level of soluble Fas (sFas) molecule, higher gene expression of sFas and decoy receptor 3 (DcR3) genes in peripheral blood mononuclear cells (PBMC) than healthy volunteers, and various alternatively spliced Fas transcripts in PBMC. The factor analysis using these results indicated that there were a small number of patients who developed immunological diseases without presenting with respiratory disorders. In addition, we discuss the mechanism involved in the development of autoimmune disorders found in silicosis patients. |
| 書誌情報 |
en : Kawasaki medical journal
巻 29,
号 1･2,
p. 33-43,
発行日 2003
|
| URL |
|
|
識別子 |
http://igakkai.kms-igakkai.com/wp/wp-content/uploads/2003en/29(1.2)33-43.2003.PDF.pdf |
|
識別子タイプ |
URI |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.11482/KMJ-E29(1/2)033 |
| ISSN |
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|
収録物識別子タイプ |
PISSN |
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収録物識別子 |
0385-0234 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-3404 |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00710169 |
| 雑誌書誌ID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12029005 |
| 著者版フラグ |
|
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出版タイプ |
VoR |
KJ00000010579.pdf (946.4 kB)
